Evidence map›Paper›PMID 24096823›Full record

ReviewBone marrow transplantation2014

Application of machine learning algorithms for clinical predictive modeling: a data-mining approach in SCT.

R Shouval, O Bondi, H Mishan, A Shimoni, R Unger, A Nagler

Abstract readReview
PubMed Publisher
In one paragraph

Review in Bone marrow transplantation, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  7. Harnessing network pharmacology in drug discovery: an integrated approach.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
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  17. Big Data in Gastroenterology Research.International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

R Shouval1] The Division of Hematology and Bone Marrow Transplantation and Internal Medicine "F" Department, The Chaim Sheba Medical Center, Tel HaShomer, Israel [2] 2013 Pinchas Borenstein Talpiot Medical Leadership Program, The Chaim Sheba Medical Center, Tel HaShomer, Israel.
O BondiThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
H MishanThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
A ShimoniThe Division of Hematology and Bone Marrow Transplantation and Internal Medicine "F" Department, The Chaim Sheba Medical Center, Tel HaShomer, Israel.
R UngerThe Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.
A NaglerThe Division of Hematology and Bone Marrow Transplantation and Internal Medicine "F" Department, The Chaim Sheba Medical Center, Tel HaShomer, Israel.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Data collected from hematopoietic SCT (HSCT) centers are becoming more abundant and complex owing to the formation of organized registries and incorporation of biological data. Typically, conventional statistical methods are used for the development of outcome prediction models and risk scores. However, these analyses carry inherent properties limiting their ability to cope with large data sets with multiple variables and samples. Machine learning (ML), a field stemming from artificial intelligence, is part of a wider approach for data analysis termed data mining (DM). It enables prediction in complex data scenarios, familiar to practitioners and researchers. Technological and commercial applications are all around us, gradually entering clinical research. In the following review, we would like to expose hematologists and stem cell transplanters to the concepts, clinical applications, strengths and limitations of such methods and discuss current research in HSCT. The aim of this review is to encourage utilization of the ML and DM techniques in the field of HSCT, including prediction of transplantation outcome and donor selection.

Indexed as

AlgorithmsArtificial IntelligenceData MiningHematopoietic Stem Cell TransplantationComputational BiologyDecision TreesHematologyHumansNeural Networks, ComputerReproducibility of ResultsStem Cell TransplantationSupport Vector Machine

Identifiers

PMID24096823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.