ReviewJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2013
Tissue-engineered skin substitutes: an overview.
Review in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Novel dermis niche equivalent based on a 3D-structure fabricated by 2-photon polymerization.Biomaterials and biosystems · 2026Article
- Collagen metabolism and incisional hernia recurrence: a comparative study between oncologic and non-oncologic patients.Journal of medicine and life · 2025Article
- Update on Hypermetabolism in Pediatric Burn Patients.Seminars in plastic surgery · 2024Review
- Comparison of combination skin substitutes and skin grafts versus skin grafts only for treating wounds measured by Vancouver Scar Scale: A comprehensive meta-analysis.SAGE open medicine · 2024Review
- Article
- Preparation and characterization of gelatin-polysaccharide composite hydrogels for tissue engineering.PeerJ · 2021Article
- Regenerative Engineering: Current Applications and Future Perspectives.Frontiers in surgery · 2021Review
- HA-g-CS Implant and Moderate-intensity Exercise Stimulate Subchondral Bone Remodeling and Promote Repair of Osteochondral Defects in Mice.International journal of medical sciences · 2021Article
- Development of a polyvinyl alcohol/sodium alginate hydrogel-based scaffold incorporating bFGF-encapsulated microspheres for accelerated wound healing.Scientific reports · 2020Article
- Bovine Decellularized Amniotic Membrane: Extracellular Matrix as Scaffold for Mammalian Skin.Polymers · 2020Article
- Article
- Human papillomavirus type 16 E6 and E7 oncoproteins interact with the nuclear p53-binding protein 1 in an in vitro reconstructed 3D epithelium: new insights for the virus-induced DNA damage response.Virology journal · 2018Article
- Subpopulations of dermal skin fibroblasts secrete distinct extracellular matrix: implications for using skin substitutes in the clinic.The British journal of dermatology · 2018Article
- Two Methods for Decellularization of Plant Tissues for Tissue Engineering Applications.Journal of visualized experiments : JoVE · 2018Article
- Article
- Electrospun Polycaprolactone/Aloe Vera_Chitosan Nanofibrous Asymmetric Membranes Aimed for Wound Healing Applications.Polymers · 2017Article
- Fabrication and Applications of Micro/Nanostructured Devices for Tissue Engineering.Nano-micro letters · 2017Review
- Quantitative monitoring of laser-treated engineered skin using optical coherence tomography.Biomedical optics express · 2016Article
- Hair Follicle Morphogenesis in the Treatment of Mouse Full-Thickness Skin Defects Using Composite Human Acellular Amniotic Membrane and Adipose Derived Mesenchymal Stem Cells.Stem cells international · 2016Article
- Burn wound healing and treatment: review and advancements.Critical care (London, England) · 2015Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Extensive skin loss and chronic wounds are still a significant challenge to clinicians: even if injured epidermis is normally able to self-renew, deep injuries can cause negative regulation of the wound healing cascade, leading to chronic wound formation. Skin-autografting surgical procedures are often limited by the poor availability of healthy tissue, whereas the use of non-self-tissues for allografts presents some severe risks. Tissue-engineered skin substitutes have recently become viable as a suitable alternative to auto- and allografts. However, biologists, biochemists, and technical engineers are still struggling to produce complex skin substitutes that can readily be transplanted in large quantities. The ambitious goal is now to construct a dermoepidermal substitute that rapidly vascularizes and optimally supports a stratifying epidermal graft on a biodegradable matrix. This review analyzes these aspects in light of the available literature and the authors' experience.
Indexed as
Identifiers
24096542What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.