Evidence map›Paper›PMID 24096190›Full record

ReviewNeuroscience and biobehavioral reviews2013

Age, plasticity, and homeostasis in childhood brain disorders.

Maureen Dennis, Brenda J Spiegler, Jenifer J Juranek, Erin D Bigler, O Carter Snead, Jack M Fletcher

Open access · greenAbstract readReview
In one paragraph

Review in Neuroscience and biobehavioral reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 4 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 4 syntheses or guidelines pooled it, 118 citations in OpenAlex.

  1. Pooled it
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  5. Objective evaluation of fusional vergence after a vision therapy protocol in typical binocular vision.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2025
    Trial
  6. Trial
  7. Article
  8. Social Determinants of Health, the developing brain, and risk and resilience for psychopathology.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
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  10. Article
  11. Review
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  14. Inpatient outcomes in pediatric diffuse axonal injury: high mortality in severe TBI and limited impact of Grade III DAI.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2025
    Article
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  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Maureen DennisProgram in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto Department of Surgery, Faculty of Medicine, University of Toronto, Toronto, ON M5G 1X8, Canada. Electronic address: maureen.dennis@sickkids.ca.
Brenda J Spiegler
Jenifer J Juranek
Erin D Bigler
O Carter Snead
Jack M Fletcher
University of Toronto · CABrigham Young University · USThe University of Texas Health Science Center at Houston · USUniversity of Houston · US

Funding

SUBJECT RECRUITMENT AND EVALUATION COREP01HD035946 · NICHD · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI FLETCHER, JACK M · 1998 to 2009
$10.8M
NICHD NIH HHS 1R01 HD04946NICHD NIH HHS P01 HD035946
6 · The paper itself

Abstract

It has been widely accepted that the younger the age and/or immaturity of the organism, the greater the brain plasticity, the young age plasticity privilege. This paper examines the relation of a young age to plasticity, reviewing human pediatric brain disorders, as well as selected animal models, human developmental and adult brain disorder studies. As well, we review developmental and childhood acquired disorders that involve a failure of regulatory homeostasis. Our core arguments are as follows:

Indexed as

AgingBrain DiseasesChildHomeostasisHumansNeuronal PlasticityAge at brain injuryChildhood-acquired brain damageHomeostasisNeurodevelopmental disordersPlasticityTime since brain injury

Identifiers

PMID24096190
PMCPMC3859812
OpenAlexW1972548059

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.