Evidence map›Paper›PMID 24095162›Full record

ReviewCurrent opinion in immunology2013

Emerging antigens involved in allergic responses.

Thomas A E Platts-Mills, Scott P Commins

Open access · greenAbstract readReview
In one paragraph

Review in Current opinion in immunology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.2field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 23 citations in OpenAlex.

  1. Tick Saliva and the Alpha-Gal Syndrome: Finding a Needle in a Haystack.Frontiers in cellular and infection microbiology · 2021
    Review
  2. Article
  3. Immunobiology of Acquired Resistance to Ticks.Frontiers in immunology · 2020
    Review
  4. Review
  5. Article
  6. Review
  7. Allergens, sources, particles, and molecules: Why do we make IgE responses?Allergology international : official journal of the Japanese Society of Allergology · 2015
    Review
  8. Review
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Thomas A E Platts-MillsDepartment of Medicine, Division of Allergy and Immunology, University of Virginia Health System, Charlottesville, VA, USA. Electronic address: tap2z@virginia.edu.
Scott P Commins
University of Virginia Health System · US

Funding

INTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2M
DUST MITE, COCKROACH AND CAT ALLERGENS IN HOUSES/ASTHMAR01AI020565 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI PLATTS-MILLS, THOMAS A. · 1985 to 2017
$7.1M
Delayed anaphylaxis to beef and pork: mechanisms and causes of a new food allergyR21AI087985 · NIAID · UNIVERSITY OF VIRGINIA · PI COMMINS, SCOTT PALMER, PLATTS-MILLS, THOMAS A. · 2010 to 2011
$422k
NIAID NIH HHS K08 AI1085190NIAID NIH HHS R01 AI020565NIAID NIH HHS R01 AI20565NIAID NIH HHS R21 AI087985NIAID NIH HHS R21 AI87985NIAID NIH HHS T32 AI007496
6 · The paper itself

Abstract

New allergic diseases can 'emerge' because of exposure to a novel antigen, because the immune responsiveness of the subject changes, or because of a change in the behavior of the population. Novel antigens have entered the environment as new pests in the home (e.g., Asian lady beetle or stink bugs), in the diet (e.g., prebiotics or wheat isolates), or because of the spread of a biting arthropod (e.g., ticks). Over the last few years, a significant new disease has been identified, which has changed the paradigm for food allergy. Bites of the tick, Amblyomma americanum, are capable of inducing IgE antibodies to galactose-alpha-1,3-galactose, which is associated with two novel forms of anaphylaxis. In a large area of the southeastern United States, the disease of delayed anaphylaxis to mammalian meat is now common. This disease challenges many previous rules about food allergy and provides a striking model of an emerging allergic disease.

Indexed as

AllergensAnimalsGlycosylationHumansHypersensitivityImmunoglobulin EMeatTick BitesAllergensImmunoglobulin E

Identifiers

PMID24095162
PMCPMC3984453
OpenAlexW2065606736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.