ArticleAsian Pacific journal of tropical biomedicine2013
Screening and characterization of extracelluar L-asparaginase producing Bacillus subtilis strain hswx88, isolated from Taptapani hotspring of Odisha, India.
Article in Asian Pacific journal of tropical biomedicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed.
- Description of a Novel Species Quadrisphaera endophytica sp. nov., a Potential Strain as a Plant Growth Promotor and Comparative Genome Analysis of the Genus Quadrisphaera.Current microbiology · 2026Article
- Chroococcus turigidus, a novel cyanobacterial source for l-sparaginase production.Scientific reports · 2025Article
- Isolation, Identification, and Characterization of L-asparaginase-Producing Human Commensal Bacterial Strains: A Promising Next-Gen Probiotics.Applied biochemistry and biotechnology · 2025Article
- Endophytic Fungi as a Promising Source of Anticancer L-Asparaginase: A Review.Current microbiology · 2023Review
- Characterization and applications of glutaminase free L-asparaginase from indigenous Bacillus halotolerans ASN9.PloS one · 2023Article
- Production and Anticancer Activity of an L-Asparaginase from Bacillus licheniformis Isolated from the Red Sea, Saudi Arabia.Scientific reports · 2019Article
- L-asparaginase production in the pseudomonas pseudoalcaligenes strain JHS-71 isolated from Jooshan Hot-spring.Molecular biology research communications · 2016Article
- Optimization of Culture Conditions for Production of the Anti-Leukemic Glutaminase Free L-Asparaginase by Newly Isolated Streptomyces olivaceus NEAE-119 Using Response Surface Methodology.BioMed research international · 2015Article
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3 authors.
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Abstract
objectiveTo screen and isolate an eco-friendly, a thermophilic and potent L-asparaginase producing bacterium, with novel immunological properties that may obviates hypersensitivity reactions.
methodsIn the present study bacterial strain isolated for extracellular L-asparaginase production from hotspring, identified by morphological, biochemical and physiological tests followed by 16S rDNA technology and the L-asparaginase production ability was tested by both semi quantitative and quantitative enzymatic assay.
resultsThe bacterial strain was identified as Bacillus subtilis strain hswx88 (GenBank Accession Number: JQ237656.1). The extracellular enzyme yielding capacity isolate Bacillus subtilis strain hswx88 (23.8 IU/mL) was found to be 1.7 and 14.5 times higher than the reference organism Pectobacterium carotovorum MTCC 1428 (14.2 IU/mL) and Bacillus sp. BCCS 034 (1.64 IU/mL).
conclusionThe isolate is eco-friendly and useful to produce bulk quantity of extracellular, thermophilic L-asparaginase for the treatment of various tumor cases and for preparation of acrylamide free fry food preparation.
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