ReviewJournal of pain research2013
Advances in cortical modulation of pain.
Review in Journal of pain research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 46 citations in OpenAlex.
- TRPC4/TRPC5 are critical for neuronal modulation by transcranial focused ultrasound in retrosplenial cortex in male mice.Nature communications · 2026Article
- Differential modulation of aversive signaling by expectation across the cingulate cortex.bioRxiv : the preprint server for biology · 2026Article
- Targeting PI3K-mTOR signaling in the anterior cingulate cortex improves emotional behavior, and locomotor activity in rats with bone cancer pain.Annals of medicine and surgery (2012) · 2025Article
- Pain- and depression-related regional homogeneity changes in ankylosing spondylitis: a functional magnetic resonance imaging study.Frontiers in neurology · 2025Article
- A Pilot Study of Functional Brain Magnetic Resonance Imaging in BPS/IC Patients: Evidence of Central Sensitization.Urology research & practice · 2024Article
- Contributions of aversive environmental stress to migraine chronification: Research update of migraine pathophysiology.World journal of clinical cases · 2021Review
- Parallel cortical-brainstem pathways to attentional analgesia.NeuroImage · 2021Article
- Salience network functional connectivity is spatially heterogeneous across sensorimotor cortex in healthy humans.NeuroImage · 2020Article
- Ultrafast ultrasound imaging pattern analysis reveals distinctive dynamic brain states and potent sub-network alterations in arthritic animals.Scientific reports · 2020Article
- Astroglial changes in the zona incerta in response to motor cortex stimulation in a rat model of chronic neuropathy.Scientific reports · 2020Article
- Altered Brain Functional Hubs and Connectivity Underlie Persistent Somatoform Pain Disorder.Frontiers in neuroscience · 2019Article
- Brain Response to Non-Painful Mechanical Stimulus to Lumbar Spine.Brain sciences · 2018Article
- The functional and structural alterations of the striatum in chronic spontaneous urticaria.Scientific reports · 2018Article
- Altered resting-state intra- and inter- network functional connectivity in patients with persistent somatoform pain disorder.PloS one · 2017Article
- Altered Spontaneous Activity in Patients with Persistent Somatoform Pain Disorder Revealed by Regional Homogeneity.PloS one · 2016Article
- Chronic musculoskeletal pain: review of mechanisms and biochemical biomarkers as assessed by the microdialysis technique.Journal of pain research · 2014Review
- Morphometric changes over the whole brain in caffeine-containing combination-analgesic-overuse headache.Molecular painArticle
- Altered intra- and inter-network functional activity among migraine, chronic migraine, and trigeminal neuralgia.Molecular painArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pain is an intricate phenomenon composed of not only sensory-discriminative aspects but also of emotional, cognitive, motivational, and affective components. There has been ample evidence for the existence of an extensive cortical network associated with pain processing over the last few decades. This network includes the anterior cingulate cortex, forebrain, insular cortex, ventrolateral orbital cortex, somatosensory cortex, occipital cortex, retrosplenial cortex, motor cortex, and prefrontal cortex. Diverse neurotransmitters participate in the cortical circuits associated with pain processing, including glutamate, gamma-aminobutyric acid, dopamine, and opioids. This work examines recent rodent studies about cortical modulation of pain, mainly at a molecular level.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.