Evidence map›Paper›PMID 24092852›Full record

ReviewClinical microbiology reviews2013

Pathogenesis and current approaches to control of varicella-zoster virus infections.

Anne A Gershon, Michael D Gershon

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03862092 (Frequency of Putative Enteric Zoster Diagnosed Using Saliva Samples in Patients With Abdominal Pain), which is not on this map. Cited by 113 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
113citing papers in PubMed, 5 pooled it
9.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03862092 nacompletednot on this mapstarted 2019, after this paper: background citation

Frequency of Putative Enteric Zoster Diagnosed Using Saliva Samples in Patients With Abdominal Pain: a Prospective Study

TypeinterventionalSponsorAsan Medical CenterRan2019 to 2019Enrolled50ConditionsAbdominal Pain, Zoster With Other ComplicationsArmsSalivary VZV-DNA PCR
3 · Its place in the literature

Who cites it

113 citing papers in PubMed, 5 syntheses or guidelines pooled it, 227 citations in OpenAlex.

  1. Pooled it
  2. Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2021
    Pooled it
  3. Vaccines for measles, mumps, rubella, and varicella in children.The Cochrane database of systematic reviews · 2020
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Quality of Life Impact of an Adjuvanted Recombinant Zoster Vaccine in Adults Aged 50 Years and Older.The journals of gerontology. Series A, Biological sciences and medical sciences · 2019
    Trial
  9. Trial
  10. Trial
  11. Vaccination Targeting Native Receptors to Enhance the Function and Proliferation of Chimeric Antigen Receptor (CAR)-Modified T Cells.Clinical cancer research : an official journal of the American Association for Cancer Research · 2017
    Trial
  12. Development of mRNA vaccines against herpes zoster.Human vaccines & immunotherapeutics · 2026
    Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Disseminated Visceral Varicella Presenting as Gastric Ulcers.European journal of case reports in internal medicine · 2026
    Article
  19. Article
  20. Article

53 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Anne A GershonDepartments of Pediatrics and Pathology and Cell Biology, Columbia University College of Physicians and Surgeons, New York, New York, USA.
Michael D Gershon
Columbia University · US

Funding

VZV in the enteric nervous system: pathogenesis and consequencesR01DK093094 · NIDDK · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MICHAEL D GERSHON, Anne A. Gershon · 2011 to 2026
$5.9M
NIDDK NIH HHS R01 DK093094
6 · The paper itself

Abstract

Varicella-zoster virus (VZV) was once thought to be a fairly innocuous pathogen. That view is no longer tenable. The morbidity and mortality due to the primary and secondary diseases that VZV causes, varicella and herpes zoster (HZ), are significant. Fortunately, modern advances, including an available vaccine to prevent varicella, a therapeutic vaccine to diminish the incidence and ameliorate sequelae of HZ, effective antiviral drugs, a better understanding of VZV pathogenesis, and advances in diagnostic virology have made it possible to control VZV in the United States. Occult forms of VZV-induced disease have been recognized, including zoster sine herpete and enteric zoster, which have expanded the field. Future progress should include development of more effective vaccines to prevent HZ and a more complete understanding of the consequences of VZV latency in the enteric nervous system.

Indexed as

ChickenpoxChickenpox VaccineHerpes ZosterHerpes Zoster VaccineAgedAntiviral AgentsChild, PreschoolClinical Trials as TopicHerpesvirus 3, HumanHumansMiddle AgedUnited StatesVaccines, AttenuatedVirus ActivationVirus LatencyAntiviral AgentsChickenpox VaccineHerpes Zoster VaccineVaccines, Attenuated

Identifiers

PMID24092852
PMCPMC3811230
OpenAlexW2158693133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.