ArticleThe Journal of antimicrobial chemotherapy2014
Effect of subinhibitory concentrations of four commonly used biocides on the conjugative transfer of Tn916 in Bacillus subtilis.
Article in The Journal of antimicrobial chemotherapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 60 citations in OpenAlex.
- Biosynthetic Gene Cluster Mining and In Vitro Evaluation of the Antimicrobial and Cytotoxic Potential ofBiology · 2026Article
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- Disruption of Pseudomonas aeruginosa Adherent Cells by NaCl and NaOCl in Drinking Water.Current microbiology · 2023Article
- Key Role of Transconjugants for Dissemination of the Integrative Conjugative Element ICEJournal of bacteriology · 2022Article
- Degradation of Bacterial Antibiotic Resistance Genes during Exposure to Non-Thermal Atmospheric Pressure Plasma.Antibiotics (Basel, Switzerland) · 2022Review
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- Biocide-tolerance and antibiotic-resistance in community environments and risk of direct transfers to humans: Unintended consequences of community-wide surface disinfecting during COVID-19?Environmental pollution (Barking, Essex : 1987) · 2021Review
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- Antibacterial activity of Xenorhabdus and Photorhabdus isolated from entomopathogenic nematodes against antibiotic-resistant bacteria.PloS one · 2020Article
- Promoter activity of ORF-less gene cassettes isolated from the oral metagenome.Scientific reports · 2019Article
- Adaptive bacterial response to low level chlorhexidine exposure and its implications for hand hygiene.Microbial cell (Graz, Austria) · 2019Review
- Antibiotic ResistanceCan Be Enhanced in Gram-Positive Species by Some Biocidal Agents Used for Disinfection.Antibiotics (Basel, Switzerland) · 2019Review
- Article
- An assessment of health management practices and occupational health hazards in tiger shrimp (Veterinary and animal science · 2018Article
- Environmental factors influencing the development and spread of antibiotic resistance.FEMS microbiology reviews · 2018Review
- The use of minimum selectable concentrations (MSCs) for determining the selection of antimicrobial resistant bacteria.Ecotoxicology (London, England) · 2017Article
- Metal stressors consistently modulate bacterial conjugal plasmid uptake potential in a phylogenetically conserved manner.The ISME journal · 2017Article
- Screening of the Antimicrobial Activity against Drug Resistant Bacteria ofFrontiers in microbiology · 2017Article
- An inquiry-based laboratory module to promote understanding of the scientific method and bacterial conjugation.Journal of microbiology & biology education · 2014Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
objectivesLarge amounts of biocides are used to reduce and control bacterial growth in the healthcare sector, food production and agriculture. This work explores the effect of subinhibitory concentrations of four commonly used biocides (ethanol, hydrogen peroxide, chlorhexidine digluconate and sodium hypochlorite) on the conjugative transposition of the mobile genetic element Tn916.
methodsConjugation assays were carried out between Bacillus subtilis strains. The donor containing Tn916 was pre-exposed to subinhibitory concentrations of each biocide for a defined length of time, which was determined by an analysis of the transcriptional response of the promoter upstream of tet(M) using β-glucuronidase reporter assays.
resultsEthanol significantly (P = 0.01) increased the transfer of Tn916 by 5-fold, whereas hydrogen peroxide, chlorhexidine digluconate and sodium hypochlorite did not significantly affect the transfer frequency.
conclusionsThese results suggest that exposure to subinhibitory concentrations of ethanol may induce the transfer of Tn916-like elements and any resistance genes they contain.
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