Evidence map›Paper›PMID 24092627›Full record

ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2014

The impact of a community-based clinical trial educational intervention among underrepresented Chinese Americans.

Grace X Ma, Yin Tan, Natasha C Blakeney, Brenda F Seals, Xiang S Ma, Shumenghui Zhai, Amy Liu, Yanfei Tai, Margo Michaels

Open access · bronzeAbstract read
In one paragraph

Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
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  12. Overcoming Barriers: Evidence-Based Strategies to Increase Enrollment of Underrepresented Populations in Cancer Therapeutic Clinical Trials-a Narrative Review.Journal of cancer education : the official journal of the American Association for Cancer Education · 2020
    Review
  13. Article
  14. Educating Hispanics About Clinical Trials and Biobanking.Journal of cancer education : the official journal of the American Association for Cancer Education · 2019
    Article
  15. Article
  16. Training Needs of Clinical and Research Professionals to Optimize Minority Recruitment and Retention in Cancer Clinical Trials.Journal of cancer education : the official journal of the American Association for Cancer Education · 2019
    Article
  17. Article
  18. Cancer Health Literacy and Willingness to Participate in Cancer Research and Donate Bio-Specimens.International journal of environmental research and public health · 2018
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Grace X MaAuthors' Affiliations: Center for Asian Health, Department of Public Health, College of Health Professions, School of Medicine, Temple University; Asian Health Trilogy, Philadelphia, Pennsylvania; Education Network to Advance Cancer Clinical Trials (NACCT), Bethesda, Maryland; and Boston University School of Public Health, Boston, Massachusetts.
Yin Tan
Natasha C Blakeney
Brenda F Seals
Xiang S Ma
Shumenghui Zhai
Amy Liu
Yanfei Tai
Margo Michaels
Boston University · US

Funding

Training ProgramU54CA153513 · NCI · TEMPLE UNIV OF THE COMMONWEALTH · PI MA, GRACE X. · 2010 to 2015
$5.2M
NCI NIH HHS 1U54CA153513-01NCI NIH HHS U54 CA153513
6 · The paper itself

Abstract

backgroundClinical trials are a critical resource for the discovery of new prevention, diagnostic, and treatment methods for cancer. The most effective prevention and treatment modalities are based on previous clinical trial results. However, participation in clinical trials is underrepresented by racial/ethnic minority populations, Asian Americans in particular. Asian Americans are the least represented of any ethnic groups in clinical trials. The purpose of this study is to develop and evaluate a culturally and linguistically appropriate community-based educational intervention to increase knowledge of and intent to participate in cancer clinical trials among underrepresented Chinese Americans.

methodsCommunity-Based Participatory Research approach was used to guide the development, cultural tailoring, implementation, and evaluation of clinical trial intervention. First, 22 Asian community representatives were recruited as community health educators (CHE) who received 12-hour training on clinical trial education. Second, 262 members were recruited from 11 Chinese community organizations. Of those recruited, a total of 247 eligible Chinese enrolled and participated in the clinical trial education delivered by trained CHEs. Participants completed pretest before and posttest after the intervention.

resultsFifteen of 21 measures of clinical trial knowledge showed significant changes post the intervention (P < 0.05). Education remained the sole demographic factor increasing clinical trial knowledge in multivariate analysis.

conclusionClinical trial education should emphasize both benefits to science and the larger Asian community. This community-based clinical trial intervention demonstrated promising results and has potential to enhance recruitment and participation in clinical trial research among the underrepresented Asian Americans. IMPACT: Improving clinical trial participation in the fast-growing Asian American population is key to dissemination of health innovations targeted to diminish health disparities.

Indexed as

AsianAgedAged, 80 and overChinaCommunity-Based Participatory ResearchFemaleHealth EducationHealth Knowledge, Attitudes, PracticeHumansMaleNeoplasmsPatient Education as TopicRandomized Controlled Trials as TopicTreatment Outcome

Identifiers

PMID24092627
PMCPMC3951588
OpenAlexW2109480635

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.