ArticleAmerican journal of epidemiology2014
Type 2 diabetes and the risk of colorectal adenomas: Black Women's Health Study.
Article in American journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Type 2 diabetes mellitus and risk of colorectal adenoma: a meta-analysis of observational studies.BMC cancer · 2016Pooled it
- Colorectal Cancer Risk and Protective Factors Among People of African Descent: A Systematic Review and Meta-Analysis.Cureus · 2025Review
- Clinical significance of colonoscopy before laparoscopic bariatric/metabolic surgery in Japanese patients.Surgery today · 2024Article
- Correlation between High Incidence of Colorectal Neoplastic Polyps and High-risk Adenomas in Patients with Diabetes Mellitus: A Retrospective Study.Endocrine, metabolic & immune disorders drug targets · 2024Article
- Age-Specific Differences in the Risk of Colorectal Precursor Lesions Among Patients with Type 2 Diabetes Undergoing Surveillance Colonoscopy.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Type 2 diabetes and the risk of colorectal polyps: A retrospective nationwide population-based study.Medicine · 2021Observational
- Impact of type 2 diabetes on adenoma detection in screening colonoscopies performed in disparate populations.World journal of clinical cases · 2021Article
- Obesity is an initiator of colon adenomas but not a promoter of colorectal cancer in the Black Women's Health Study.Cancer causes & control : CCC · 2020Article
- Differential relationship between colorectal cancer and diabetes in a nationally representative sample of adults.Journal of diabetes and its complications · 2018Article
- Diabetes mellitus and hyperglycemia control on the risk of colorectal adenomatous polyps: a retrospective cohort study.BMC family practice · 2018Article
- Different effects of metformin and insulin on primary and secondary chemoprevention of colorectal adenoma in diabetes type 2: Traditional and Bayesian meta-analysis.EXCLI journal · 2018Article
- Diabetes-induced mechanophysiological changes in the small intestine and colon.World journal of diabetes · 2017Review
- Colorectal cancer screening and prevention in women.Digestive diseases and sciences · 2015Review
- Re: "Type 2 diabetes and the risk of colorectal adenomas: Black Women's Health Study". Four authors reply.American journal of epidemiology · 2014Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
5 authors.
Funding
Abstract
Evidence for the association of type 2 diabetes mellitus (DM) with colorectal neoplasms is contradictory, and African Americans have been underrepresented in the studies published to date. In a nested case-control study (1995-2009), we examined DM and insulin therapy as risk factors for colorectal adenomas in African American women enrolled in the ongoing Black Women's Health Study. From women reporting ever having undergone a gastrointestinal endoscopy, 917 cases of colorectal adenoma were compared with 2,751 controls without a colorectal polyp, matched on age and follow-up time. Cases were verified by medical record review. We used multivariable logistic regression analyses that included DM exposures and selected confounders. There were no overall associations between DM and adenoma risk or between insulin use and adenoma risk. However, DM without insulin use was inversely associated with risk of colon adenomas (odds ratio (OR) = 0.71, 95% confidence interval (CI): 0.52, 0.97) but not rectal adenomas. DM was inversely associated with adenoma risk in women older than 55 years (OR = 0.64, 95% CI: 0.44, 0.91) but not in women 55 years or younger (OR = 1.24, 95% CI: 0.81, 1.89). Future research should attempt to replicate the unexpected inverse association of DM with colon adenoma risk among older African American women.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.