Evidence map›Paper›PMID 24091725›Full record

ArticleScientific reports2013

A new class of animal collagen masquerading as an insect silk.

Tara D Sutherland, Yong Y Peng, Holly E Trueman, Sarah Weisman, Shoko Okada, Andrew A Walker, Alagacone Sriskantha, Jacinta F White, Mickey G Huson, Jerome A Werkmeister and 5 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 5 institutions in 1 country.

Tara D SutherlandCSIRO Ecosystem Sciences, Clunies Ross Street, Acton, ACT, 2601, Australia.
Yong Y Peng
Holly E Trueman
Sarah Weisman
Shoko Okada
Andrew A Walker
Alagacone Sriskantha
Jacinta F White
Mickey G Huson
Jerome A Werkmeister
Veronica Glattauer
Violet Stoichevska
Stephen T Mudie
Victoria S Haritos
John A M Ramshaw
Commonwealth Scientific and Industrial Research Organisation · AUMaterials Science & Engineering · AUCSIRO Manufacturing · AUEcosystem Sciences · AUAustralian Synchrotron · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Collagen is ubiquitous throughout the animal kingdom, where it comprises some 28 diverse molecules that form the extracellular matrix within organisms. In the 1960s, an extracorporeal animal collagen that forms the cocoon of a small group of hymenopteran insects was postulated. Here we categorically demonstrate that the larvae of a sawfly species produce silk from three small collagen proteins. The native proteins do not contain hydroxyproline, a post translational modification normally considered characteristic of animal collagens. The function of the proteins as silks explains their unusual collagen features. Recombinant proteins could be produced in standard bacterial expression systems and assembled into stable collagen molecules, opening the door to manufacture a new class of artificial collagen materials.

Indexed as

InsectaAmino Acid SequenceAnimalsBiomechanical PhenomenaCollagenEscherichia coliGene ExpressionHydroxyprolineInsect ProteinsMolecular Sequence DataRecombinant ProteinsSequence AlignmentSilkX-Ray DiffractionCollagenHydroxyprolineInsect ProteinsRecombinant ProteinsSilk

Identifiers

PMID24091725
PMCPMC3790195
OpenAlexW2018329919

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.