Evidence map›Paper›PMID 24091131›Full record

ArticleJournal of pediatric nursing

Variation in antibiotic susceptibility of uropathogens by age among ambulatory pediatric patients.

Jessina C McGregor, Yennie Quach, David T Bearden, David H Smith, Susan E Sharp, Judith A Guzman-Cottrill

Abstract read
In one paragraph

Article in Journal of pediatric nursing. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. The Emerging Resistance in Nosocomial Urinary Tract Infections: From the Pediatrics Perspective.Mediterranean journal of hematology and infectious diseases · 2018
    Article
  6. Antibiotic Resistance in Pediatric Urinary Tract Infections.Current infectious disease reports · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jessina C McGregorDepartment of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, Portland, OR. Electronic address: mcgregoj@ohsu.edu.
Yennie QuachDepartment of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, Portland, OR.
David T BeardenDepartment of Pharmacy Practice, College of Pharmacy, Oregon State University/Oregon Health & Science University, Portland, OR.
David H SmithCenter for Health Research, Kaiser Permanente Northwest, Portland, OR.
Susan E SharpDepartment of Pathology, Clinical Microbiology Laboratory, Regional Laboratory, Kaiser Permanente Northwest, Portland, OR.
Judith A Guzman-CottrillDepartment of Pediatrics, Oregon Health & Science University, CDRCP, Portland, OR.
Kaiser Permanente · USOregon Health & Science University · USOregon State University · US

Funding

Oregon Clinical and Translational Science InstituteKL2RR024141 · NCRR · OREGON HEALTH & SCIENCE UNIVERSITY · PI ORWOLL, ERIC S. · 2006 to 2011
$3.6M
Oregon Clinical and Translational Research InstituteKL2TR000152 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI ELLISON, DAVID H · 2012 to 2015
$1.7M
NCATS NIH HHS KL2 TR000152NCRR NIH HHS KL2 RR024141NCRR NIH HHS KL2RR024141
6 · The paper itself

Abstract

We compared uropathogen antibiotic susceptibility across age groups of ambulatory pediatric patients. For Escherichia coli (n=5,099) and other Gram-negative rods (n=626), significant differences (p<0.05) existed across age groups for ampicillin, cefazolin, and trimethoprim/sulfamethoxazole susceptibility. In E. coli, differences in trimethoprim/sulfamethoxazole susceptibility varied from 79% in children under 2 to 88% in ages 16-18 (p<0.001), while ampicillin susceptibility varied from 30% in children under 2 to 53% in ages 2-5 (p=0.015). Uropathogen susceptibility to common urinary anti-infectives may be lower in the youngest children. Further investigation into these differences is needed to facilitate appropriate and prudent treatment of urinary tract infections.

Indexed as

Drug Resistance, BacterialAdolescentAmbulatory CareAmpicillinAnti-Bacterial AgentsCefazolinChildChild, PreschoolFemaleHumansMaleMicrobial Sensitivity TestsRetrospective StudiesTrimethoprim, Sulfamethoxazole Drug CombinationUrinary Tract InfectionsUropathogenic Escherichia coliAmpicillinAnti-Bacterial AgentsCefazolinTrimethoprim, Sulfamethoxazole Drug CombinationAmbulatory careAntibiotic resistanceUrinary tract infection

Identifiers

PMID24091131
PMCPMC3943820
OpenAlexW2059139232

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.