ArticleJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2013
Age-specific and sex-specific morbidity and mortality from avian influenza A(H7N9).
Article in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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Who cites it
19 citing papers in PubMed, 29 citations in OpenAlex.
- Age-specific mortality patterns across influenza pandemics: evidence from all-cause mortality data across multiple populations.International journal of epidemiology · 2026Article
- Progression and Trends in Virus from Influenza A to COVID-19: An Overview of Recent Studies.Viruses · 2021Review
- Vital Members in the More Dysbiotic Oropharyngeal Microbiotas in H7N9-Infected Patients.Frontiers in medicine · 2020Article
- Sex and sex steroids impact influenza pathogenesis across the life course.Seminars in immunopathology · 2019Review
- Impacts of age and gender at the risk of underlying medical conditions and death in patients with avian influenza A (H7N9): a meta-analysis study.Therapeutics and clinical risk management · 2018Article
- TMPRSS2: A potential target for treatment of influenza virus and coronavirus infections.Biochimie · 2017Review
- Age and testosterone mediate influenza pathogenesis in male mice.American journal of physiology. Lung cellular and molecular physiology · 2016Article
- Limited Antigenic Diversity in Contemporary H7 Avian-Origin Influenza A Viruses from North America.Scientific reports · 2016Article
- MERS coronavirus: diagnostics, epidemiology and transmission.Virology journal · 2015Review
- Prognosis and survival of 128 patients with severe avian influenza A(H7N9) infection in Zhejiang province, China.Epidemiology and infection · 2015Article
- Middle East respiratory syndrome: An emerging coronavirus infection tracked by the crowd.Virus research · 2015Review
- Household transmissibility of avian influenza A (H7N9) virus, China, February to May 2013 and October 2013 to March 2014.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2015Article
- A confirmed severe case of human infection with avian-origin influenza H7N9: A case report.Experimental and therapeutic medicine · 2015Article
- Pandemic potential of avian influenza A (H7N9) viruses.Trends in microbiology · 2014Review
- Major emerging and re-emerging zoonoses in China: a matter of global health and socioeconomic development for 1.3 billion.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2014Review
- Assessing the pandemic potential of emerging influenza.The Lancet. Infectious diseases · 2014Article
- Identification of Influenza A/H7N9 virus infection-related human genes based on shortest paths in a virus-human protein interaction network.BioMed research international · 2014Article
- Emerging respiratory viral infections: MERS-CoV and influenza.The Lancet. Respiratory medicine · 2014Article
- Cross-conservation of T-cell epitopes: now even more relevant to (H7N9) influenza vaccine design.Human vaccines & immunotherapeutics · 2014Review
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We used data on age and sex for 136 laboratory confirmed human A(H7N9) cases reported as of 11 August 2013 to compare age-specific and sex-specific patterns of morbidity and mortality from the avian influenza A(H7N9) virus with those of the avian influenza A(H5N1) virus. Human A(H7N9) cases exhibit high degrees of age and sex bias: mortality is heavily biased toward males >50 years, no deaths have been reported among individuals <25 years old, and relatively few cases documented among children or adolescents. The proportion of fatal cases (PFC) for human A(H7N9) cases as of 11 August 2013 was 32%, compared to a cumulative PFC for A(H5N1) of 83% in Indonesia and 36% in Egypt. Approximately 75% of cases of all A(H7N9) cases occurred among individuals >45 years old. Morbidity and mortality from A(H7N9) are lowest among individuals between 10 and 29 years, the age group which exhibits the highest cumulative morbidity and case fatality rates from A(H5N1). Although individuals <20 years old comprise nearly 50% of all human A(H5N1) cases, only 7% of all reported A(H7N9) cases and no deaths have been reported among individuals in this age group. Only 4% of A(H7N9) cases occurred among children<5 years old, and only one case from the 10 to 20 year age group. Age- and sex-related differences in morbidity and mortality from emerging zoonotic diseases can provide insights into ecological, economic, and cultural factors that may contribute to the emergence and proliferation of novel zoonotic diseases in human populations.
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