Evidence map›Paper›PMID 24090834›Full record

ArticleBiomaterials2013

A dual sensor for real-time monitoring of glucose and oxygen.

Liqiang Zhang, Fengyu Su, Sean Buizer, Hongguang Lu, Weimin Gao, Yanqing Tian, Deirdre Meldrum

Open access · greenAbstract read
In one paragraph

Article in Biomaterials, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

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  15. A polymer-based ratiometric intracellular glucose sensor.Chemical communications (Cambridge, England) · 2014
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Liqiang ZhangCenter for Biosignatures Discovery Automation, Biodesign Institute, Arizona State University, Tempe 85287-6501, USA.
Fengyu Su
Sean Buizer
Hongguang Lu
Weimin Gao
Yanqing Tian
Deirdre Meldrum
Arizona State University · US

Funding

CEGSTech: Integrated Biologically-Active MicrosystemsP50HG002360 · NHGRI · UNIVERSITY OF WASHINGTON · PI MELDRUM, DEIRDRE R. · 2001 to 2012
$37.8M
Live-cell Microarray for high-throughput observation of metabolic signaturesU01CA164250 · NCI · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI MELDRUM, DEIRDRE R. · 2011 to 2013
$2.1M
NCI NIH HHS 5 U01 CA164250NCI NIH HHS U01 CA164250NHGRI NIH HHS 5 P50 HG002360NHGRI NIH HHS P50 HG002360
6 · The paper itself

Abstract

A dual glucose and oxygen sensor in a polymer format was developed. The dual sensor composed of a blue emitter as the glucose probe, a red emitter as an oxygen probe, and a yellow emitter as a built-in reference probe which does not respond to either glucose or oxygen. All the three probes were chemically immobilized in a polyacrylamide-based matrix. Therefore, the dual sensor possesses three well separated emission colors and ratiometric approach is applicable for analysis of the glucose and oxygen concentration at biological conditions. The sensor was applied for real-time monitoring of glucose and oxygen consumption of bacterial cells, Escherichia coli (E. coli) and Bacillus subtilis (B. subtilis), and mammalian cells of mouse macrophage J774 and human cervical cancer HeLa cell lines. On the other hand, in order to achieve satisfactory sensing performance for glucose, compositions of the matrices among poly(2-hydroxyethyl methacrylate), polyacrylamide, and poly(6-aminohexyl methacrylamide) which is a linker polymer for grafting the glucose probe, were optimized.

Indexed as

Biosensing TechniquesAcrylic ResinsAnimalsBacillus subtilisCell LineEscherichia coliGlucoseHeLa CellsHumansMiceMolecular StructureOxygenPolyacrylamidesAcrylic ResinsGlucoseOxygenPolyacrylamidesDual sensorGlucose sensorOxygen sensorRatiometricSensor

Identifiers

PMID24090834
PMCPMC3878311
OpenAlexW1972035720

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.