Evidence map›Paper›PMID 24090092›Full record

ArticleExpert review of respiratory medicine2013

Perinatal factors in neonatal and pediatric lung diseases.

Rodney D Britt, Arij Faksh, Elizabeth Vogel, Richard J Martin, Christina M Pabelick, Y S Prakash

Open access · greenAbstract read
In one paragraph

Article in Expert review of respiratory medicine, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 49 citations in OpenAlex.

  1. Cigarette smoke enhances proliferation and extracellular matrix deposition by human fetal airway smooth muscle.American journal of physiology. Lung cellular and molecular physiology · 2014
    Trial
  2. Article
  3. Review
  4. Article
  5. Exogenous hydrogen sulfide attenuates hyperoxia effects on neonatal mouse airways.American journal of physiology. Lung cellular and molecular physiology · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Cellular clocks in hyperoxia effects on [CaAmerican journal of physiology. Lung cellular and molecular physiology · 2021
    Article
  11. Review
  12. Article
  13. Review
  14. Neurotrophin Regulation and Signaling in Airway Smooth Muscle.Advances in experimental medicine and biology · 2021
    Article
  15. Article
  16. Hydrogen sulfide, oxygen, and calcium regulation in developing human airway smooth muscle.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2020
    Article
  17. Hyperoxia-induced Cellular Senescence in Fetal Airway Smooth Muscle Cells.American journal of respiratory cell and molecular biology · 2019
    Article
  18. Caveolin-1 scaffolding domain peptide prevents hyperoxia-induced airway remodeling in a neonatal mouse model.American journal of physiology. Lung cellular and molecular physiology · 2019
    Article
  19. Cellular senescence in the lung across the age spectrum.American journal of physiology. Lung cellular and molecular physiology · 2019
    Review
  20. Pneumonia.Seminars in fetal & neonatal medicine · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Rodney D BrittDepartment of Physiology and Biomedical Engineering, 4-184 W Jos SMH, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA.
Arij Faksh
Elizabeth Vogel
Richard J Martin
Christina M Pabelick
Y S Prakash
Mayo Clinic · USMayo Clinic in Arizona · USRainbow Babies & Children's Hospital · US

Funding

NEURAL REGULATION OF AIRWAYS DURING POSTNATAL MATURATIONR01HL056470 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 1996 to 2025
$10.5M
Neurotrophins in the LungR01HL088029 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S. · 2009 to 2022
$5.9M
Interdisciplinary Training in Lung Physiology and Biomedical EngineeringT32HL105355 · NHLBI · MAYO CLINIC ROCHESTER · PI PRAKASH, Y. S., SIECK, GARY C. · 2012 to 2021
$3.9M
NHLBI NIH HHS R01 HL056470NHLBI NIH HHS R01 HL088029NHLBI NIH HHS T32 HL105355
6 · The paper itself

Abstract

Wheezing and asthma are significant clinical problems for infants and young children, particularly following premature birth. Recurrent wheezing in infants can progress to persistent asthma. As in adults, altered airway structure (remodeling) and function (increased bronchoconstriction) are also important in neonatal and pediatric airway diseases. Accumulating evidence suggests that airway disease in children is influenced by perinatal factors including perturbations in normal fetal lung development, postnatal interventions in the intensive care unit (ICU) and environmental and other insults in the neonatal period. Here, in addition to genetics, maternal health, environmental processes, innate immunity and impaired lung development/function can all influence pathogenesis of airway disease in children. We summarize current understanding of how prenatal and postnatal factors can contribute to development of airway diseases in neonates and children. Understanding these mechanisms will help identify and develop novel therapies for childhood airway diseases.

Indexed as

Age FactorsAirway RemodelingAsthmaBronchoconstrictionChildChild, PreschoolDisease ProgressionHumansInfantInfant, NewbornLungPrognosisRespiratory SoundsRisk Factors

Identifiers

PMID24090092
PMCPMC4109979
OpenAlexW2128412773

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.