ArticleInternational journal of endocrinology2013
Relationship between Testicular Volume and Conventional or Nonconventional Sperm Parameters.
Article in International journal of endocrinology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
45 citing papers in PubMed, 2 syntheses or guidelines pooled it, 112 citations in OpenAlex.
- The first Australian evidence-based guidelines on male infertility.The Medical journal of Australia · 2025Guideline
- Ultrasound evaluation of varicoceles: systematic literature review and rationale of the ESUR-SPIWG Guidelines and Recommendations.Journal of ultrasound · 2020Pooled it
- Eight Days of Water-Only Fasting Promotes Favorable Changes in the Functioning of the Urogenital System of Middle-Aged Healthy Men.Nutrients · 2020Trial
- Preoperative Total Testicular Volume as a Predictor of Total Motile Sperm Count Improvement Following Microsurgical Varicocelectomy.Andrology · 2026Article
- Ultrasound localisation microscopy tracks testicular microvascular adaptations to endocrine function in male infertility.EBioMedicine · 2026Article
- Defining Puberty and Spectrum of Hypogonadism in Alström Syndrome.The Journal of clinical endocrinology and metabolism · 2025Observational
- Investigating the Impact of Bismuth Oxide Nanoparticles on Dazl Gene Expression and Spermatogenesis Indices in Male Mice.Biological trace element research · 2025Article
- Differentiation between nonobstructive azoospermia and obstructive azoospermia: then and now.Asian journal of andrology · 2025Review
- Investigation of Antibody Pharmacokinetics in Male Reproductive System and Its Characterization Using a Translational PBPK Model.Antibodies (Basel, Switzerland) · 2025Article
- Predicting Semen Analysis Parameters from Testicular Ultrasonography Images Using Deep Learning Algorithms: An Innovative Approach to Male Infertility Diagnosis.Journal of clinical medicine · 2025Article
- The Importance of Discordant Follicle Stimulating Hormone and Inhibin B Levels in Primary Infertile Men: Findings from a Cross-Sectional Study.The world journal of men's health · 2025Article
- Effect of 96% Ethanol Turmeric Extract as an Antifertility Agent on the Testicular Weight of Sprague Dawley Rats.Acta medica Philippina · 2025Article
- Is testicular microlithiasis associated with decreased semen parameters? a systematic review.Basic and clinical andrology · 2024Review
- Predictive parameters of the efficacy of varicocele repair: a review.Asian journal of andrology · 2024Review
- Comparison of the gene expression profile of testicular tissue before and after sexual maturity in Qianbei Ma goats.BMC veterinary research · 2024Article
- Association between Hidradenitis Suppurativa and Abnormalities in Semen Parameters and Sexual Function: A Pilot Study.Acta dermato-venereologica · 2023Article
- Impaired Testicular Function without Altering Testosterone Concentration Using an Anti-Follicular-Stimulating Hormone Receptor (Anti-FSHr) Single-Chain Variable Fragment (scFv) in Long-Tailed Macaques (Animals : an open access journal from MDPI · 2023Article
- Is There a Relevant Clinical Impact in Differentiating IdiopathicThe world journal of men's health · 2023Article
- Combined analysis of mRNA-miRNA from testis tissue in Tibetan sheep with different FecB genotypes.Open life sciences · 2023Article
- A first look into radiomics application in testicular imaging: A systematic review.Frontiers in radiology · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background. Reduced testicular volume (TV) (<12 cm(3)) is associated with lower testicular function. Several studies explored the conventional sperm parameters (concentration, motility, and morphology) and the endocrine function (gonadotropins and testosterone serum concentrations) in the patients with reduction of TV. No other parameters have been examined. Aim. This study aims at evaluating some biofunctional sperm parameters by flow cytometry in the semen of men with reduced TV compared with that of subjects with normal TV. Methods. 78 patients without primary scrotal disease were submitted to ultrasound evaluation of the testis. They were divided into two groups according to testicular volume: A Group, including 40 patients with normal testicular volume (TV > 15 cm(3)) and B Group, including 38 patients with reduced testicular volume (TV ≤ 12 cm(3)). All patients underwent serum hormone concentration, conventional and biofunctional (flow cytometry) sperm parameters evaluation. Results. With regard to biofunctional sperm parameters, all values (mitochondrial membrane potential, phosphatidylserine externalization, chromatin compactness, and DNA fragmentation) were strongly negatively correlated with testicular volume (P < 0.0001). Conclusions. This study for the first time in the literature states that the biofunctional sperm parameters worsen and with near linear correlation, with decreasing testicular volume.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.