Evidence map›Paper›PMID 24089253›Full record

ArticleJournal of biomedical optics2013

Photoacoustic recovery after photothermal bleaching in living cells.

Chiye Li, Chi Zhang, Liang Gao, Alejandro Garcia-Uribe, Lihong V Wang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of biomedical optics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chiye Li
Chi Zhang
Liang Gao
Alejandro Garcia-Uribe
Lihong V Wang
Washington University in St. Louis · US

Funding

Task Specific Project 3: Diffuse Optical TomographyU54CA136398 · NCI · WASHINGTON UNIVERSITY · PI MINTUN, MARK A. · 2008 to 2012
$6.0M
PHOTON TUNNELING: SHEDDING NEW LIGHT ON BIOMEDICINEDP1EB016986 · NIBIB · WASHINGTON UNIVERSITY · PI WANG, LIHONG · 2012 to 2016
$3.8M
PHOTOACOUSTIC MICROSCOPY OF NEOVASCULARIZATION IN RENAL CANCER GROWTH AND THERAPYR01CA159959 · NCI · WASHINGTON UNIVERSITY · PI ARBEIT, JEFFREY MICHAEL · 2011 to 2015
$2.9M
Monitoring of Breast Neoadjuvant Therapy by Thermo- and Photo- Acoustic TomographR01CA134539 · NCI · WASHINGTON UNIVERSITY · PI MONSEES, BARBARA, WANG, LIHONG · 2009 to 2013
$2.9M
Photoacoustic endoscopy of Barretts esophagusR01CA157277 · NCI · WASHINGTON UNIVERSITY · PI MEYERS, BRYAN F, ZHOU, QIFA · 2010 to 2014
$2.7M
NCCDPHP CDC HHS DP1 EB016986NCI NIH HHS R01 CA134539NCI NIH HHS R01 CA157277NCI NIH HHS R01 CA159959NCI NIH HHS U54 CA136398NIBIB NIH HHS DP1 EB016986
6 · The paper itself

Abstract

We present an innovative method, photoacoustic recovery after photothermal bleaching (PRAP), for studying particle dynamics at micron scale via photoacoustic imaging. As an intuitive way to visualize and quantify dynamic processes, PRAP is demonstrated first in a simple phantom study and then in a more complex measurement involving live cells. Compared with the conventional fluorescence-based approach, PRAP provides high signal-to-noise ratio (SNR) imaging with minimal bleaching-induced artifacts during the recovery stage, ideal for monitoring the diffusive and kinetic processes inside a cell.

Indexed as

PhotobleachingAnimalsCell SurvivalCytological TechniquesDiffusionGoldKineticsMetal NanoparticlesMiceMicroscopy, AcousticNIH 3T3 CellsPhantoms, ImagingPhotoacoustic TechniquesSignal-To-Noise RatioGold

Identifiers

PMID24089253
PMCPMC3788654
OpenAlexW2168820238

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.