Trial reportThe American journal of clinical nutrition2013
Experimental sleep curtailment causes wake-dependent increases in 24-h energy expenditure as measured by whole-room indirect calorimetry.
Trial report in The American journal of clinical nutrition, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 48 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The SLuMBER Study: The Sleep Lengthening and Metabolic Health, Body Composition, Energy Balance and Cardiovascular Risk Study
Impact of Sleep Restriction on Cardiometabolic Risk Factors in Pre vs Postmenopausal Women
Who cites it
48 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Obstructive sleep apnea and energy balance regulation: A systematic review.Sleep medicine reviews · 2017Pooled it
- The effects of partial sleep deprivation on energy balance: a systematic review and meta-analysis.European journal of clinical nutrition · 2017Pooled it
- A systematic review and meta-analysis of randomized controlled trials of the impact of sleep duration on adiposity and components of energy balance.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2015Pooled it
- Impact of sleep restriction on biomarkers of thyroid function: Two pooled randomized trials.Sleep medicine · 2024Trial
- Effects of ad libitum food intake, insufficient sleep and weekend recovery sleep on energy balance.Sleep · 2021Trial
- Influence of sleep restriction on weight loss outcomes associated with caloric restriction.Sleep · 2018Trial
- Effect of shortened sleep on energy expenditure, core body temperature, and appetite: a human randomised crossover trial.Scientific reports · 2017Trial
- Phenotypic Stability of Energy Balance Responses to Experimental Total Sleep Deprivation and Sleep Restriction in Healthy Adults.Nutrients · 2016Trial
- Sleep Restriction Enhances the Daily Rhythm of Circulating Levels of Endocannabinoid 2-Arachidonoylglycerol.Sleep · 2016Trial
- Resting metabolic rate varies by race and by sleep duration.Obesity (Silver Spring, Md.) · 2015Trial
- Oxalic acid and diacylglycerol 36:3 are cross-species markers of sleep debt.Proceedings of the National Academy of Sciences of the United States of America · 2015Trial
- Postprandial thermogenesis and substrate oxidation are unaffected by sleep restriction.International journal of obesity (2005) · 2014Trial
- Sex and race differences in caloric intake during sleep restriction in healthy adults.The American journal of clinical nutrition · 2014Trial
- Energy constraint on human health.Trends in endocrinology and metabolism: TEM · 2026Review
- Prolonged Short Sleep and Its Effect on Body Weight and Composition : A Pooled Analysis of Randomized Trials.Annals of internal medicine · 2026Observational
- Examining the Role of Sleep in Body Weight Regulation and Implications for Obesity Treatment: A Narrative Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Review
- Deep rest: An integrative model of how contemplative practices combat stress and enhance the body's restorative capacity.Psychological review · 2024Article
- Review
- A single night of moderate at-home sleep restriction increases hunger and food intake in overweight young adults.Nutrition (Burbank, Los Angeles County, Calif.) · 2023Article
- The energetic cost of allostasis and allostatic load.Psychoneuroendocrinology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundEpidemiologic evidence has shown a link between short sleep and obesity. Clinical studies suggest a role of increased energy intake in this relation, whereas the contributions of energy expenditure (EE) and substrate utilization are less clearly defined.
objectiveOur aim was to investigate the effects of sleep curtailment on 24-h EE and respiratory quotient (RQ) by using whole-room indirect calorimetry under fixed-meal conditions.
designTen females aged 22-43 y with a BMI (in kg/m²) of 23.4-27.5 completed a randomized, crossover study. Participants were studied under short- (4 h/night) and habitual- (8 h/night) sleep conditions for 3 d, with a 4-wk washout period between visits. Standardized weight-maintenance meals were served at 0800, 1200, and 1900 with a snack at 1600. Measures included EE and RQ during the sleep episode on day 2 and continuously over 23 h on day 3.
resultsShort compared with habitual sleep resulted in significantly higher (± SEM) 24-h EE (1914.0 ± 62.4 compared with 1822.1 ± 43.8 kcal; P = 0.012). EE during the scheduled sleep episode (0100-0500 and 2300-0700 in short- and habitual-sleep conditions, respectively) and across the waking episode (0800-2300) were unaffected by sleep restriction. RQ was unaffected by sleep restriction.
conclusionsShort compared with habitual sleep is associated with an increased 24-h EE of ~92 kcal (~5%)--lower than the increased energy intake observed in prior sleep-curtailment studies. This finding supports the hypothesis that short sleep may predispose to weight gain as a result of an increase in energy intake that is beyond the modest energy costs associated with prolonged nocturnal wakefulness.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.