Observational studyJournal of clinical hypertension (Greenwich, Conn.)2013
Increased aortic stiffness and related factors in patients with peripheral arterial disease.
Observational study in Journal of clinical hypertension (Greenwich, Conn.), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07169045 (Examination of the Validity and Reliability of 6-minute Stepper Test in Patients With Peripheral Artery Disease), which is not on this map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Examination of the Validity and Reliability of 6-minute Stepper Test in Patients With Peripheral Artery Disease
Who cites it
16 citing papers in PubMed.
- Risk Stratification of Patients with Peripheral Arterial Disease and Abdominal Aortic Aneurysm Using Aortic Augmentation Index.PloS one · 2015Trial
- Article
- Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease.American journal of physiology. Heart and circulatory physiology · 2024Review
- Paradox of the Relationship between Cardio-Ankle Vascular Index and Ankle-Brachial Index in Patients with Lower Extremity Artery Disease.Annals of vascular diseases · 2023Article
- Oscillometric measurement of the ankle-brachial index and the estimated carotid-femoral pulse wave velocity improves the sensitivity of an automated device in screening peripheral artery disease.Frontiers in cardiovascular medicine · 2023Article
- A Nomogram for Predicting the Risk of Critical Limb Ischemia in Adults with Hypertension: A Retrospective Study.International journal of general medicine · 2022Article
- Traditional and non-traditional risk factors for peripheral artery disease development/progression in patients with type 2 diabetes: the Rio de Janeiro type 2 diabetes cohort study.Cardiovascular diabetology · 2021Observational
- Arterial stiffness and 5-year mortality in patients with peripheral arterial disease.Journal of human hypertension · 2020Article
- Applications of arterial stiffness markers in peripheral arterial disease.Jornal vascular brasileiro · 2019Review
- Diabetic cardiomyopathy: prevalence, determinants and potential treatments.Therapeutic advances in endocrinology and metabolism · 2019Review
- Oxidative Stress and Arterial Dysfunction in Peripheral Artery Disease.Antioxidants (Basel, Switzerland) · 2018Review
- Peripheral vascular disease assessment in the lower limb: a review of current and emerging non-invasive diagnostic methods.Biomedical engineering online · 2018Review
- Arterial stiffness and subendocardial viability ratio in patients with peripheral arterial disease.Journal of clinical hypertension (Greenwich, Conn.) · 2018Article
- Peripheral vascular disease is associated with increased pulse wave velocity and augmentation index: clinical implications.Journal of clinical hypertension (Greenwich, Conn.) · 2014Article
- Aortic augmentation index in patients with peripheral arterial disease.Journal of clinical hypertension (Greenwich, Conn.) · 2014Article
- Arterial stiffness in patients with peripheral arterial disease.Journal of clinical hypertension (Greenwich, Conn.) · 2013Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A number of conditions have been associated with functional changes of large arteries. The aim of this study was to evaluate the factors associated with aortic stiffness in patients with peripheral arterial disease (PAD). The authors studied 86 patients with PAD (ankle-brachial pressure index [ABPI] ≤0.9) and 86 controls. Aortic stiffness was determined by pulse wave velocity (aPWV) using applanation tonometry. In PAD patients, aPWV was higher compared with controls (11 ± 3 vs 9.8 ± 1.8; P=.002). In multiple regression analysis, aPWV was independently associated with pulse pressure (β=0.05, P=.01) in the PAD patients and with age in the control group (β=0.08, P=.0005). The results of this study confirm an aPWV increase in patients with PAD and emphasize the association between blood pressure and aPWV. Further studies are necessary to assess whether higher aortic stiffening adds prognostic value to ABPI, which is the most powerful prognostic indicator in PAD.
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