ArticleJournal of natural products2013
Chlorinated coumarins from the polypore mushroom Fomitopsis officinalis and their activity against Mycobacterium tuberculosis.
Article in Journal of natural products, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Polypore mushroom mycelia as an adjunct to COVID-19 vaccination: a randomized clinical trial.BMC immunology · 2026Trial
- Adaptive resilience: agarikon mycelium modulates immune responses and provides oxidative stress buffering in human immune cells.Frontiers in immunology · 2026Article
- Mycochemistry, Traditional Uses, and Nutraceutical Potential of Laricifomes officinalis: A Biotechnological and Pharmacological Perspective.Plant foods for human nutrition (Dordrecht, Netherlands) · 2025Review
- The bioactive compounds, beneficial medicinal properties, and biotechnological prospects ofFrontiers in cellular and infection microbiology · 2025Review
- Identification of a Novel Coumarins Biosynthetic Pathway in the Endophytic Fungus Fusarium oxysporum GU-7 with Antioxidant Activity.Applied and environmental microbiology · 2023Article
- Naturally Occurring Organohalogen Compounds-A Comprehensive Review.Progress in the chemistry of organic natural products · 2023Review
- The Synthesis and Evaluation of Aminocoumarin Peptidomimetics as Cytotoxic Agents on Model BacterialMaterials (Basel, Switzerland) · 2021Article
- Article
- Coumarin Derivatives as New Toxic Compounds to Selected K12, R1-R4Materials (Basel, Switzerland) · 2020Article
- Bioassay-guided purification of sesquiterpenoids from the fruiting bodies ofRSC advances · 2019Article
- Antimicrobial properties ofMycology · 2019Review
- Lanostane triterpenoids from Fomitopsis officinalis and their trypanocidal activity.Journal of natural medicines · 2018Article
- Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways.Molecules (Basel, Switzerland) · 2017Article
- Fungal strain matters: colony growth and bioactivity of the European medicinal polyporesAMB Express · 2015Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
An EtOH extract of the polypore mushroom Fomitopsis officinalis afforded two new naturally occurring chlorinated coumarins, which were identified as the previously synthesized compounds 6-chloro-4-phenyl-2H-chromen-2-one (1) and ethyl 6-chloro-2-oxo-4-phenyl-2H-chromen-3-carboxylate (2). The structures of the two isolates were deduced by ab initio spectroscopic methods and confirmed by chemical synthesis. In addition, an analogue of each was synthesized as 7-chloro-4-phenyl-2H-chromen-2-one (3) and ethyl 7-chloro-2-oxo-4-phenyl-2H-chromen-3-carboxylate (4). All four compounds were characterized physicochemically, and their antimicrobial activity profiles revealed a narrow spectrum of activity with lowest MICs against the Mycobacterium tuberculosis complex.
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