ArticlePloS one2013
Influenza transmission in a cohort of households with children: 2010-2011.
Article in PloS one, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
51 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Non-pharmaceutical interventions to reduce influenza transmission in households: a systematic review and meta-analysis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2025Pooled it
- Trial
- Insights Into monoclonal antibodies and vaccines targeting respiratory viruses.Frontiers in pediatrics · 2026Review
- Multiplex serology reveals age-specific immunodynamics of respiratory pathogens in the wake of the COVID-19 pandemic.Nature communications · 2025Article
- Rigorous methodological approaches to address knowledge gaps in exercise, nutrition, immunity, and infection risk research.Physiological reports · 2025Review
- Multiplex serology reveals age-specific immunodynamics of endemic respiratory pathogens in the wake of the COVID-19 pandemic.medRxiv : the preprint server for health sciences · 2025Article
- Estimating the generation time for influenza transmission using household data in the United States.Epidemics · 2025Article
- Author's response: Viral load decline time offers theoretical insight rather than practical value.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- Inferring transmission risk of respiratory viral infection from the viral load kinetics of SARS-CoV-2, England, 2020 to 2021 and influenza A virus, Hong Kong, 2008 to 2012.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2025Article
- A Natural Disaster Exacerbates and Redistributes Disease Risk Among Free-Ranging Macaques by Altering Social Structure.Ecology letters · 2025Article
- Effectiveness of cocoon strategy vaccination on prevention of influenza-like illness in young infants.Human vaccines & immunotherapeutics · 2024Article
- Influenza virus shedding and symptoms: Dynamics and implications from a multiseason household transmission study.PNAS nexus · 2024Article
- Estimating the generation time for influenza transmission using household data in the United States.medRxiv : the preprint server for health sciences · 2024Article
- Risk mapping of respiratory viral transmission and disease severity using individual and environmental health parameters: A scoping review and protocol analysis.One health (Amsterdam, Netherlands) · 2024Review
- Seroprevalence of Protective Antibodies Against Influenza and the Reduction of the Influenza Incidence Rate: An Annual Repeated Cross-Sectional Study From 2014 to 2019.Influenza and other respiratory viruses · 2024Article
- Transmission dynamics of seasonal influenza in a remote island population.Scientific reports · 2023Article
- Distinct influenza surveillance networks and their agreement in recording regional influenza circulation: Experience from Southeast Michigan.Influenza and other respiratory viruses · 2022Article
- Household transmission of influenza A and B within a prospective cohort during the 2013-2014 and 2014-2015 seasons.Statistics in medicine · 2021Article
- Clinical and virological outcomes with baloxavir compared with oseltamivir in pediatric patients aged 6 to < 12 years with influenza: an open-label, randomized, active-controlled trial protocol.BMC infectious diseases · 2021Article
- SARS-CoV-2 Infection in Health Care Personnel and Their Household Contacts at a Tertiary Academic Medical Center: Protocol for a Longitudinal Cohort Study.JMIR research protocols · 2021Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
backgroundHouseholds play a major role in community spread of influenza and are potential targets for mitigation strategies.
methodsWe enrolled and followed 328 households with children during the 2010-2011 influenza season; this season was characterized by circulation of influenza A (H3N2), A (H1N1)pdm09 and type B viruses. Specimens were collected from subjects with acute respiratory illnesses and tested for influenza in real-time reverse transcriptase polymerase chain reaction (RT-PCR) assays. Influenza cases were classified as community-acquired or household-acquired, and transmission parameters estimated.
resultsInfluenza was introduced to 78 (24%) households and transmission to exposed household members was documented in 23 households. Transmission was more likely in younger households (mean age <22 years) and those not reporting home humidification, but was not associated with household vaccination coverage. The secondary infection risk (overall 9.7%) was highest among young children (<9 years) and varied substantially by influenza type/subtype with the highest risk for influenza A (H3N2). The serial interval (overall 3.2 days) also varied by influenza type and was longest for influenza B. Duration of symptomatic illness was shorter in children compared with adults, and did not differ by influenza vaccination status. DISCUSSION: Prospective study of households with children over a single influenza season identified differences in household transmission by influenza type/subtype, subject age, and home humidification, suggesting possible targets for interventions to reduce transmission.
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