ReviewMammalian genome : official journal of the International Mammalian Genome Society2014
The NIMH Research Domain Criteria (RDoC) Project: implications for genetics research.
Review in Mammalian genome : official journal of the International Mammalian Genome Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
34 citing papers in PubMed.
- Dimensional and transdiagnostic phenotypes in psychiatric genome-wide association studies.Molecular psychiatry · 2023Review
- Charting the Landscape of Genetic Overlap Between Mental Disorders and Related Traits Beyond Genetic Correlation.The American journal of psychiatry · 2022Article
- Revisiting the seven pillars of RDoC.BMC medicine · 2022Article
- Reduction of DNMT3a and RORA in the nucleus accumbens plays a causal role in post-traumatic stress disorder-like behavior: reversal by combinatorial epigenetic therapy.Molecular psychiatry · 2021Article
- Rhythm and timing as vulnerabilities in neurodevelopmental disorders.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2021Review
- FireMaster® 550 (FM 550) exposure during the perinatal period impacts partner preference behavior and nucleus accumbens core medium spiny neuron electrophysiology in adult male and female prairie voles, Microtus ochrogaster.Hormones and behavior · 2021Article
- Large-scale collaboration in ENIGMA-EEG: A perspective on the meta-analytic approach to link neurological and psychiatric liability genes to electrophysiological brain activity.Brain and behavior · 2021Article
- Insufficient Evidence for "Autism-Specific" Genes.American journal of human genetics · 2020Review
- Extreme-groups designs in studies of dimensional phenomena: Advantages, caveats, and recommendations.Journal of abnormal psychology · 2020Article
- Pharmacogenetics and Depression: A Critical Perspective.Psychiatry investigation · 2019Article
- The necessity, validity, and clinical utility of a new diagnostic entity: Acute suicidal affective disturbance.Journal of clinical psychology · 2019Article
- Children's biobehavioral reactivity to challenge predicts DNA methylation in adolescence and emerging adulthood.Developmental science · 2019Article
- Psychophysiological correlates between emotional response inhibition and posttraumatic stress symptom clusters.Scientific reports · 2018Article
- De novo variant of TRRAP in a patient with very early onset psychosis in the context of non-verbal learning disability and obsessive-compulsive disorder: a case report.BMC medical genetics · 2018Article
- Focusing on the Differences of Resting-State Brain Networks, Using a Data-Driven Approach to Explore the Functional Neuroimaging Characteristics of Extraversion Trait.Frontiers in neuroscience · 2018Article
- Connecting Openness and the Resting-State Brain Network: A Discover-Validate Approach.Frontiers in neuroscience · 2018Article
- Symptom modelling can be influenced by psychiatric categories: choices for research domain criteria (RDoC).Theoretical medicine and bioethics · 2017Article
- brain-coX: investigating and visualising gene co-expression in seven human brain transcriptomic datasets.Genome medicine · 2017Article
- Development of a Diverse Learning Experience for Diverse Psychiatry Resident Needs: A Four-Year Biological Psychiatry Curriculum Incorporating Principles of Neurobiology, Psychopharmacology, and Evidence-Based Practice.Psychiatry investigation · 2017Article
- The genetics of anxiety-related negative valence system traits.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2017Review
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heterogeneity of disorders, comorbidity across diagnoses, and reification of existing disease classifications are some of the challenges facing psychiatry in the twenty-first century. NIMH's Research Domain Criteria (RDoC) Project seeks to address these issues by defining basic dimensions of function that cut across disorders as traditionally defined and can be studied across multiple units of analysis, from genes to neural circuits to behaviors. The intent is to translate rapid progress in basic genetic, neurobiological, and behavioral research to an improved integrative understanding of psychopathology. In so doing, RDoC seeks to facilitate the development of new and/or optimally targeted treatments for mental disorders. The RDoC project would not have been possible without NIMH's long-term investment in basic research. Without the continuation of basic research, both related and unrelated to current RDoC domains and constructs, it will not be possible to sustain the RDoC effort. This article seeks to outline the relationship between RDoC and NIMH's ongoing support for broad-based basic research, from genetics to behavior.
Indexed as
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24085332What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.