ReviewThe Journal of clinical investigation2013
Pharmacological agents currently in clinical trials for disorders in neurogastroenterology.
Review in The Journal of clinical investigation, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 31 citations in OpenAlex.
- Microbiota-Gut-Brain Axis Dysregulation in Alzheimer's Disease: Multi-Pathway Effects and Therapeutic Potential.Aging and disease · 2024Review
- Herbal Therapies in Functional Gastrointestinal Disorders: A Narrative Review and Clinical Implication.Frontiers in psychiatry · 2020Review
- Cardiovascular safety of prokinetic agents: A focus on drug-induced arrhythmias.Neurogastroenterology and motility · 2018Review
- Oral treatment with plecanatide or dolcanatide attenuates visceral hypersensitivityWorld journal of gastroenterology · 2018Article
- Adenosine AJournal of clinical medicine · 2017Review
- Identification of an analgesic lipopeptide produced by the probiotic Escherichia coli strain Nissle 1917.Nature communications · 2017Article
- Prokinetics in the Management of Functional Gastrointestinal Disorders.Current gastroenterology reports · 2017Review
- Recent Updates on the Treatment of Constipation.Intestinal research · 2015Review
- Prokinetics in the Management of Functional Gastrointestinal Disorders.Journal of neurogastroenterology and motility · 2015Article
- Intestinal secretory mechanisms in irritable bowel syndrome-diarrhea.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2015Review
- Gastric emptying and glycaemia in health and diabetes mellitus.Nature reviews. Endocrinology · 2015Review
- Validating biomarkers of treatable mechanisms in irritable bowel syndrome.Neurogastroenterology and motility · 2014Article
- Physiological underpinnings of irritable bowel syndrome: neurohormonal mechanisms.The Journal of physiology · 2014Review
- Elobixibat and its potential role in chronic idiopathic constipation.Therapeutic advances in gastroenterology · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Esophageal, gastrointestinal, and colonic diseases resulting from disorders of the motor and sensory functions represent almost half the patients presenting to gastroenterologists. There have been significant advances in understanding the mechanisms of these disorders, through basic and translational research, and in targeting the receptors or mediators involved, through clinical trials involving biomarkers and patient responses. These advances have led to relief of patients' symptoms and improved quality of life, although there are still significant unmet needs. This article reviews the pipeline of medications in development for esophageal sensorimotor disorders, gastroparesis, chronic diarrhea, chronic constipation (including opioid-induced constipation), and visceral pain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.