Evidence map›Paper›PMID 24084586›Full record

Trial reportAmerican journal of hypertension2014

The long-term effects of lifestyle change on blood pressure: One-year follow-up of the ENCORE study.

Alan L Hinderliter, Andrew Sherwood, Linda W Craighead, Pwa-Hwa Lin, Lana Watkins, Michael A Babyak, James A Blumenthal

3 registry-linked trialsAbstract readRandomized Controlled Trial
In one paragraph

Trial report in American journal of hypertension, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 43 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00571844 nacompletednot on this map

Behavioral Treatment of High Blood Pressure

TypeinterventionalSponsorDuke UniversityRan2003 to 2013Enrolled144ConditionsHypertensionArmsDASH diet, DASH diet plus Weight loss
NCT03196895 nacompletednot on this mapstarted 2017, after this paper: background citation

Treating Type 2 Diabetes by Reducing Postprandial Glucose Elevations: A Paradigm Shift in Lifestyle Modification

TypeinterventionalSponsorUniversity of VirginiaRan2017 to 2020Enrolled192ConditionsDiabetes Mellitus, Type 2ArmsWeight reduction training, PPG training, discrete BG feedback, continuous BG feedback
NCT03207893 nacompletednot on this mapstarted 2018, after this paper: background citation

Benefits of Adding Continuous Glucose Monitoring to Glycemic Load, Exercise, and Monitoring of Blood Glucose (GEM) for Adults With Type 2 Diabetes - Phase 2

TypeinterventionalSponsorUniversity of VirginiaRan2018 to 2020Enrolled24ConditionsDiabetes Mellitus, Type 2ArmsGEM lifestyle modification & continuous glucose monitoring, Routine Care
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Trial
  9. Trial
  10. Trial
  11. Trial
  12. Trial
  13. Trial
  14. Trial
  15. Article
  16. Could this be the first step towards a tailor-made lifestyle modification?Hypertension research : official journal of the Japanese Society of Hypertension · 2025
    Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alan L HinderliterDepartment of Medicine, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.
Andrew Sherwood
Linda W Craighead
Pwa-Hwa Lin
Lana Watkins
Michael A Babyak
James A Blumenthal

Funding

Pilot Project for the DTMI CRA ProgramUL1RR024128 · NCRR · DUKE UNIVERSITY · PI CALIFF, ROBERT M · 2006 to 2010
$48.1M
Behavioral Treatment of High Blood PressureR01HL074103 · NHLBI · DUKE UNIVERSITY · PI BLUMENTHAL, JAMES A · 2003 to 2008
$3.7M
NCRR NIH HHS 5UL1RR024128-03NCRR NIH HHS M01-RR-30NCRR NIH HHS UL1 RR024128NHLBI NIH HHS HL074103NHLBI NIH HHS R01 HL074103
6 · The paper itself

Abstract

backgroundThere is a paucity of data describing the sustained benefits of lifestyle interventions on health behaviors and blood pressure (BP).

methodsWe examined the persistence of changes in health habits and BP in the ENCORE study, a trial in which 144 overweight individuals with above-normal BP were randomized to one of the following 16-week interventions: Dietary Approaches to Stop Hypertension (DASH) diet alone (DASH-A), DASH diet plus a behavioral weight management intervention (DASH-WM), or Usual Care. Follow-up assessments were conducted 8 months after the end of treatment.

resultsAt 16 weeks, systolic BP was reduced by 16.1 (95% confidence interval (CI) = 13.0-19.2) mm Hg in the DASH-WM group, 11.2 (95% CI = 8.1-14.3) mm Hg in the DASH-A group, and 3.4 (95% CI = 0.4-6.4) mm Hg in the Usual Care group. A decrease in BP persisted for 8 months, with systolic BP lower than baseline by 11.7 (95% CI = 8.1-15.3) mm Hg in the DASH-WM group, 9.5 (95% CI = 6.7-12.1) mm Hg in the DASH-A group, and 3.9 (95% CI = 0.5-7.3) mm Hg in the Usual Care group (P < 0.001 for active treatments vs. Usual Care). DASH-WM subjects lost 8.7 kg during the intervention and remained 6.3 kg lighter on follow-up examination. Changes in diet content were sustained in both DASH intervention groups. Among those who participated in DASH-WM, however, caloric intake was no longer lower, and only 21% reported still exercising regularly 8 months after completing the intervention.

conclusionsChanges in dietary habits, weight, and BP persisted for 8 months after completion of the 16-week ENCORE program, with some attenuation of the benefits. Additional research is needed to identify effective methods to promote long-term maintenance of the benefits of lifestyle modification programs. CLINICAL

trial registrationClinicaltrials.gov identifier: NCT00571844.

Indexed as

Blood PressureLife StyleRisk Reduction BehaviorAdultCaloric RestrictionCognitive Behavioral TherapyExercise TherapyFeeding BehaviorFemaleHealth BehaviorHealth Knowledge, Attitudes, PracticeHumansHypertensionMaleMiddle AgedNorth Carolinablood pressureDASH dietexercisehypertension

Identifiers

PMID24084586
PMCPMC3978946

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.