Evidence map›Paper›PMID 24084025›Full record

ArticleMolecules (Basel, Switzerland)2013

Glycosyl-Nucleolipids as new bioinspired amphiphiles.

Laurent Latxague, Amit Patwa, Eric Amigues, Philippe Barthélémy

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Rational preparation and application of a mRNA delivery system with cytidinyl/cationic lipid.Journal of controlled release : official journal of the Controlled Release Society · 2021
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laurent LatxagueINSERM U869, Bordeaux, F-33076, France. philippe.barthelemy@inserm.fr.
Amit Patwa
Eric Amigues
Philippe Barthélémy

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Four new Glycosyl-NucleoLipid (GNL) analogs featuring either a single fluorocarbon or double hydrocarbon chains were synthesized in good yields from azido thymidine as starting material. Physicochemical studies (surface tension measurements, differential scanning calorimetry) indicate that hydroxybutanamide-based GNLs feature endothermic phase transition temperatures like the previously reported double chain glycerol-based GNLs. The second generation of GNFs featuring a free nucleobase reported here presents a better surface activity (lower glim) compared to the first generation of GNFs.

Indexed as

Calorimetry, Differential ScanningClick ChemistryGlucoseNucleosidesSurface-Active AgentsSurface TensionZidovudineGlucoseNucleosidesSurface-Active AgentsZidovudine

Identifiers

PMID24084025
PMCPMC6270249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.