Evidence map›Paper›PMID 24083892›Full record

ArticleEarly human development2013

Diagnosis and treatment of pulmonary hypertension in infancy.

Robin H Steinhorn

Abstract read
In one paragraph

Article in Early human development, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 45 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Observational
  8. A Review of Oxygen Physiology and Appropriate Management of Oxygen Levels in Premature Neonates.Advances in neonatal care : official journal of the National Association of Neonatal Nurses · 2018
    Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Antenatal BAY 41-2272 reduces pulmonary hypertension in the rabbit model of congenital diaphragmatic hernia.American journal of physiology. Lung cellular and molecular physiology · 2016
    Article
  18. Article
  19. Common respiratory conditions of the newborn.Breathe (Sheffield, England) · 2016
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Robin H SteinhornDepartment of Pediatrics, University of California Davis Children's Hospital, Sacramento, CA, United States. Electronic address: robin.steinhorn@ucdmc.ucdavis.edu.
UC Davis Children's Hospital · US

Funding

REDOX REGULATION IN THE PERINATAL PULMONARY VASCULATURER01HL054705 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI STEINHORN, ROBIN H. · 2001 to 2013
$4.8M
NHLBI NIH HHS R01 HL054705
6 · The paper itself

Abstract

Normal pulmonary vascular development in infancy requires maintenance of low pulmonary vascular resistance after birth, and is necessary for normal lung function and growth. The developing lung is subject to multiple genetic, pathological and/or environmental influences that can adversely affect lung adaptation, development, and growth, leading to pulmonary hypertension. New classifications of pulmonary hypertension are beginning to account for these diverse phenotypes, and or pulmonary hypertension in infants due to PPHN, congenital diaphragmatic hernia, and bronchopulmonary dysplasia (BPD). The most effective pharmacotherapeutic strategies for infants with PPHN are directed at selective reduction of PVR, and take advantage of a rapidly advancing understanding of the altered signaling pathways in the remodeled vasculature.

Indexed as

BosentanBronchopulmonary DysplasiaHernia, DiaphragmaticHumansHypertension, PulmonaryInfant, NewbornMilrinoneNitric OxidePiperazinesProstaglandinsPurinesSignal TransductionSildenafil CitrateSulfonamidesSulfonesVascular ResistanceBosentanMilrinoneNitric OxidePiperazinesProstaglandinsPurinesSildenafil CitrateSulfonamidesSulfones

Identifiers

PMID24083892
PMCPMC4464839
OpenAlexW2100830383

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.