Evidence map›Paper›PMID 24083879›Full record

ArticleJournal of chemotherapy (Florence, Italy)2013

Ceftaroline fosamil and treatment of acute bacterial skin and skin structure infections: CAPTURE study experience.

Paul D Santos, Amanda Davis, Alena Jandourek, Alexander Smith, H David Friedland

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Journal of chemotherapy (Florence, Italy), 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Paul D Santos
Amanda Davis
Alena Jandourek
Alexander Smith
H David Friedland
Good Samaritan Medical Center · USLakes Region General Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Clinical Assessment Program and TEFLARO Utilization Registry (CAPTURE) is a multicentre retrospective cohort study in the USA describing treatment of acute bacterial skin and skin structure infection (ABSSSI) with ceftaroline fosamil (CPT-F). Charts for review were chosen by random selection. Among 647 evaluable patients, 52% were obese, 46% had diabetes mellitus (DM), and 19% had peripheral vascular disease (PVD). Methicillin-resistant Staphylococcus aureus (MRSA) was recovered in 28% and methicillin-susceptible S. aureus (MSSA), 11%. Antibiotics were administered prior to CPT-F treatment in 80%, and concurrently in 39%. Clinical success overall was 85%; in patients with DM, 83%; with PVD, 76%; and in obese patients, 88%. Clinical success was ≥ 79% across all infection types; 81% for MRSA and 83% for MSSA; and 86% for ceftaroline monotherapy and 84% for concurrent therapy. These high clinical success rates support CPT-F as an effective treatment option for ABSSSI, including infections due to MRSA and patients with significant co-morbidities.

Indexed as

AdolescentAdultAgedAged, 80 and overCeftarolineCephalosporinsFemaleHumansMaleMethicillin-Resistant Staphylococcus aureusMiddle AgedRetrospective StudiesSkinSkin Diseases, BacterialSkin Diseases, InfectiousStaphylococcal InfectionsCeftarolineCephalosporinsABSSSI,Acute bacterial skin and skin structure infection,CAPTURE,ceftaroline fosamil,Diabetes mellitus,MRSA,ObesityPeripheral vascular disease,

Identifiers

PMID24083879
PMCPMC3878396
OpenAlexW2033526702

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.