ArticleCardiovascular diabetology2013
Lipoprotein(a) is not related to markers of insulin resistance in pregnancy.
Article in Cardiovascular diabetology, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 20 citations in OpenAlex.
- Risk of Incident Diabetes Related to Lipoprotein(a), LDL Cholesterol, and Their Changes With Alirocumab: Post Hoc Analyses of the ODYSSEY OUTCOMES Randomized Trial.Diabetes care · 2025Trial
- Lipoprotein(a) and atherosclerosis risk across estimated glucose disposal rate strata: evaluating synergistic predictive utility.Lipids in health and disease · 2026Article
- Triglycerides and HDL cholesterol as strong correlates of insulin resistance: Evidence from NHANES 2013 to 2018.Medicine · 2026Article
- Low early-pregnancy serum lipoprotein(a) as an independent associated factor for gestational diabetes mellitus: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Association between lipoprotein(a) and insulin resistance in Chinese adults: results from the China health and nutrition survey.Frontiers in endocrinology · 2023Article
- Diabetic dyslipidaemia.Practical laboratory medicine · 2021Review
- Early Prediction of Gestational Diabetes Mellitus in the Chinese Population via Advanced Machine Learning.The Journal of clinical endocrinology and metabolism · 2021Article
- Association between blood lipid level and embryo quality during in vitro fertilization.Medicine · 2020Observational
- The small dense LDL particle/large buoyant LDL particle ratio is associated with glucose metabolic status in pregnancy.Lipids in health and disease · 2017Article
- Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia.Diabetes & metabolism journal · 2015Review
- Inflammatory and Other Biomarkers: Role in Pathophysiology and Prediction of Gestational Diabetes Mellitus.International journal of molecular sciences · 2015Review
- Effects of folic acid supplementation on serum homocysteine and lipoprotein (a) levels during pregnancy.BioImpacts : BI · 2015Article
- Lipoprotein (a) and atherogenic indices in Sudanese patients with type 2 diabetes.International journal of health sciences · 2014Article
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Authors and funding
6 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDyslipidemia, a major risk factor for cardiovascular disease is a common finding in patients with type 2 diabetes and among women with gestational diabetes. Elevated levels of lipoprotein(a) [Lp(a)] are linked to increased risk of cardiovascular disease. However, its relationship with insulin resistance, type 2 diabetes and gestational diabetes is controversial and unproven. Here we aimed to clarify whether Lp(a) levels are associated with insulin sensitivity in pregnancy.
methodsSixty-four women with gestational diabetes and 165 with normal glucose tolerance were enrolled in the study. Fasting Lp(a) serum levels were measured in all women at 24-28 weeks of gestation.
resultsIn pregnancy, there was no significant difference in serum Lp(a) concentrations between the two groups. Its level did not correlate with markers of insulin resistance (HOMA-IR), insulin sensitivity (HOMA-S%), pancreatic beta-cell function (HOMA-B%) and insulin sensitivity in dynamic conditions (OGIS). In addition, fasting glucose and insulin levels and those throughout an oral glucose tolerance test were independent of Lp(a) concentrations in our study group.
conclusionsLp(a) levels in pregnant women do not differ with respect to the presence or absence of gestational diabetes. Although influenced by some components of the lipid profile, such as triglycerides and HDL-C, insulin resistance in pregnancy is not affected by Lp(a).
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