ArticleInternational journal of applied & basic medical research2013
A novel marker procalcitonin may help stem the antibiotic overuse in emergency setting.
Article in International journal of applied & basic medical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical and Cost-Effectiveness of Procalcitonin Test for Prodromal Meningococcal Disease-A Meta-Analysis.PloS one · 2015Pooled it
- Usefulness of procalcitonin (PCT), C-reactive protein (CRP), and white blood cell (WBC) levels in the differential diagnosis of acute bacterial, viral, and mycoplasmal respiratory tract infections in children.BMC pulmonary medicine · 2021Article
- One-step-immunoassay of procalcitonin enables rapid and accurate diagnosis of bacterial infection.RSC advances · 2021Article
- In Situ Growth of CuWOSensors (Basel, Switzerland) · 2019Article
- Biomarkers for sepsis: a review with special attention to India.BioMed research international · 2014Review
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The day the wonder drugs, antibiotics, were available for cure to humans; dramatic rise of average life expectancy has been recorded compared to past. However, disease-causing microbes that have developed resistance to antibiotics are an increasing public health problem. Recently, superbug emergence was reported in some countries including India. One of the reasons quoted was misuse of antibiotics. Clinical signs and symptoms of infection often do not point towards the etiology. The dilemma occurs as diagnosis of sepsis is difficult because of nonspecificity of clinical signs and symptoms, and frequent overlapping of symptoms with other noninfectious causes of systemic inflammation. Key for improving survival rates lies in early diagnosis and treatment. Serum procalcitonin (PCT) levels measuring in sick patients during infection may be valuable in diagnosing the conditions, and its changing levels have some prognostic value too.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.