ArticleJournal of AIDS & clinical research2013
Antiretroviral Therapy (ART) Side Effect Impacted on Quality of Life, and Depressive Symptomatology: A Mixed-Method Study.
Article in Journal of AIDS & clinical research, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
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Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The Role of ARV Associated Adverse Drug Reactions in Influencing Adherence Among HIV-Infected Individuals: A Systematic Review and Qualitative Meta-Synthesis.AIDS and behavior · 2017Pooled it
- Relationship Between Patient Engagement and Depressive Symptoms Among People Living With HIV in a Mobile Health Intervention: Secondary Analysis of a Randomized Controlled Trial.JMIR mHealth and uHealth · 2020Trial
- Health-related quality of life among adult cancer patients with and without HIV: Analysis of SEER-MHOS data (2007-2017).Journal of geriatric oncology · 2026Article
- Risk of Psychiatric Morbidity in People Living With Human Immunodeficiency Virus: A Population-Based Cohort Study.Psychiatry investigation · 2026Article
- Structural aspects of HIV-1 integrase inhibitors: SAR studies and synthetic strategies.Molecular diversity · 2025Review
- Sex differences in discontinuations due to side effects of second-generation integrase strand transfer inhibitors: a systematic review and meta-analysis.EClinicalMedicine · 2025Article
- Depressive Symptoms Among Adolescents and Young Adults Living With HIV on Antiretroviral Therapy: Outcomes From a Cross-Sectional Study in Accra, Ghana.AIDS research and treatment · 2025Article
- How the Term 'Self-Management' is Used in HIV Research in Low- and Middle-Income Countries: A Scoping Review.AIDS and behavior · 2022Article
- Prevalence of depression and associated factors among people living with HIV/AIDS in public hospitals of Southeast Ethiopia.BMC psychiatry · 2022Article
- Longitudinal trajectory of the association between quality of life and depression among people living with HIV in China: a mixed effects model.AIDS care · 2022Article
- Baseline and Process Factors of Anti-Retroviral Therapy That Predict Loss to Follow-up Among People Living with HIV/AIDS in China: A Retrospective Cohort Study.AIDS and behavior · 2022Article
- Article
- Exploring the barriers to the antiretroviral therapy adherence among people living with HIV in Bangladesh: A qualitative approach.PloS one · 2022Article
- Associations between antiretroviral therapy-related experiences and mental health status among people living with HIV in China: a prospective observational cohort study.AIDS research and therapy · 2021Observational
- Antiretroviral therapy for HIV controllers: Reasons for initiation and outcomes in the French ANRS-CO21 CODEX cohort.EClinicalMedicine · 2021Article
- Translation and cross-cultural adaptation of WHOQOL-HIV Bref among people living with HIV/AIDS in Pakistan.Health and quality of life outcomes · 2021Article
- Understanding How Gay, Bisexual, and Other Men Who Have Sex With Men in China Cope With HIV Care-Related Stressors.AIDS education and prevention : official publication of the International Society for AIDS Education · 2021Article
- Article
- Unmet needs of symptom management and associated factors among the HIV-positive population in Shanghai, China: A cross-sectional study.Applied nursing research : ANR · 2020Article
- Changes in quality of life and its associated factors among illicit drug users in Vietnamese mountainous provinces: a 12-month follow-up study.Substance abuse treatment, prevention, and policy · 2020Article
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Authors and funding
7 authors.
Funding
Abstract
Antiretroviral therapy (ART) is known for its side effects. In this paper, we describe ART side effects as experienced by Chinese HIV+ individuals. This study presents two stages of a research project, combining qualitative in-depth interviews (29 HIV+ participants) with quantitative statistical data analysis (N = 120). All data was collected between July 2005 to March 2008 at Beijing's Ditan Hospital. Consent was obtained from each participant for the qualitative interview and again for the quantitative survey. During in-depth interviews, Chinese HIV+ patients reported experiencing digestive discomfort, skin rashes, numbness, memory loss, nightmares, and dizziness, which not only brought them physical discomfort, but also interrupted different dimensions of their social lives. Furthermore, multiple regression analyses revealed that those who reported more severe side effects also experienced greater depressive mood after controlling for other clinical and psychosocial factors. ART side effects are one of the primary reasons causing HIV+ individuals to delay or stop taking life-saving medication; therefore, clinical interventions are critically needed to assist HIV+ individuals in managing ART side effects. ART side effects reinforced existing negative attitudes toward ART and lead to lower ART adherence. Future research should focus on developing culturally sensitive interventions to enhance HIV+ self-management, to alleviate physical and psychological burden from ART and HIV.
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