SynthesiseLife2013
Phenotypic landscape inference reveals multiple evolutionary paths to C4 photosynthesis.
Synthesis in eLife, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.
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Who cites it
66 citing papers in PubMed.
- Summarizing Evolutionary Trajectories from Phylogenetic Character Maps of Discrete Traits.bioRxiv : the preprint server for biology · 2026Article
- Evolutionary inference reveals global natural histories and predicted pathways of antimicrobial resistance in Klebsiella pneumoniae.PLoS biology · 2026Article
- Inducibility of cyclic electron transport is linked to the transition from C3-C4 to C4 photosynthesis in Flaveria.Plant physiology · 2026Article
- Conserved spatial patterning of gene expression in independent lineages of CThe New phytologist · 2026Article
- Review
- A transcription factor module mediating CEMBO reports · 2025Article
- Evolutionary diversification of C2 photosynthesis in the grass genus Homolepis (Arthropogoninae).Annals of botany · 2025Article
- Genetic mapping for agronomic, nutritional, and leaf vein traits in the indigenous cropNPJ sustainable agriculture · 2025Article
- Leaf transcriptomes from C3, C3-C4 intermediate, and C4Neurachne species give insights into C4 photosynthesis evolution.Plant physiology · 2024Article
- HyperTraPS-CT: Inference and prediction for accumulation pathways with flexible data and model structures.PLoS computational biology · 2024Article
- Genomic and Transcriptomic Insights into the Evolution of C4 Photosynthesis in Grasses.Genome biology and evolution · 2024Article
- Complementing model species with model clades.The Plant cell · 2024Review
- Review
- Article
- Atmospheric CO2 decline and the timing of CAM plant evolution.Annals of botany · 2023Article
- Reconciling continuous and discrete models of C4 and CAM evolution.Annals of botany · 2023Article
- Brassicaceae display variation in efficiency of photorespiratory carbon-recapturing mechanisms.Journal of experimental botany · 2023Article
- HyperHMM: efficient inference of evolutionary and progressive dynamics on hypercubic transition graphs.Bioinformatics (Oxford, England) · 2023Article
- A scheme for CPlant molecular biology · 2022Review
- The evolution of stomatal traits along the trajectory toward C4 photosynthesis.Plant physiology · 2022Article
6 more citing papers are in PubMed but not listed here.
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4 authors.
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Abstract
C4 photosynthesis has independently evolved from the ancestral C3 pathway in at least 60 plant lineages, but, as with other complex traits, how it evolved is unclear. Here we show that the polyphyletic appearance of C4 photosynthesis is associated with diverse and flexible evolutionary paths that group into four major trajectories. We conducted a meta-analysis of 18 lineages containing species that use C3, C4, or intermediate C3-C4 forms of photosynthesis to parameterise a 16-dimensional phenotypic landscape. We then developed and experimentally verified a novel Bayesian approach based on a hidden Markov model that predicts how the C4 phenotype evolved. The alternative evolutionary histories underlying the appearance of C4 photosynthesis were determined by ancestral lineage and initial phenotypic alterations unrelated to photosynthesis. We conclude that the order of C4 trait acquisition is flexible and driven by non-photosynthetic drivers. This flexibility will have facilitated the convergent evolution of this complex trait. DOI:http://dx.doi.org/10.7554/eLife.00961.001.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.