ArticleJournal of human reproductive sciences2013
Unilateral and bilateral cryptorchidism and its effect on the testicular morphology, histology, accessory sex organs, and sperm count in laboratory mice.
Article in Journal of human reproductive sciences, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Evidence for decreasing sperm count in African population from 1965 to 2015.African health sciences · 2017Pooled it
- Microbiota contributes to regulates the external genitalia development through gut-testis axis in male geese.Poultry science · 2026Article
- Integrated ultrasonographic, endocrine, seminal, and morphological characterization of cryptorchidism in collared peccary (Animal reproduction · 2026Article
- Comparative analysis of ERK and CREB activity in normal and cryptorchid testes of bulls.Journal of veterinary science · 2025Article
- Biochemical Mechanisms That Buffer the Effects of High Temperatures in the Sand-Dwelling LizardAnimals : an open access journal from MDPI · 2025Article
- Expression of Protein Markers in Spermatogenic and Supporting Sertoli Cells Affected by High Abdominal Temperature in Cryptorchidism Model Mice.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2023Article
- The relationship between vascular endothelial growth factor and spermatogenesis disturbance in an experimentally-induced unilateral cryptorchidism murine model.Molecular biology reports · 2020Article
- Low-dose tamoxifen treatment in juvenile males has long-term adverse effects on the reproductive system: implications for inducible transgenics.Scientific reports · 2017Article
- The Disappearing Sperms: Analysis of Reports Published Between 1980 and 2015.American journal of men's health · 2017Review
- Murine model indicates 22q11.2 signaling adaptorProceedings of the National Academy of Sciences of the United States of America · 2017Article
- Influence of naturally unilateral cryptorchidism on the histomorphometry of the testes and daily sperm production in West African Dwarf goats.Iranian journal of veterinary research · 2016Article
- Co-education with Environmental Cues May Kindle Early Onset of Female Puberty.International journal of preventive medicine · 2016Article
- A Small-scale Cross-sectional Study for the Assessment of Cardiorespiratory Fitness in Relation to Body Composition and Morphometric Characters in Fishermen of Araku Valley, Andhra Pradesh, India.International journal of preventive medicine · 2014Article
- Metals and male reproduction: The possible mechanisms.Advanced biomedical research · 2014Article
- Correlation of common biochemical markers for bone turnover, serum calcium, and alkaline phosphatase in post-menopausal women.The Malaysian journal of medical sciences : MJMS · 2014Article
- Current trends of male reproductive health disorders and the changing semen quality.International journal of preventive medicine · 2014Article
- Is Mind-Body Relaxation By Yoga is Effective to Combat with Lifestyle Stress?Annals of medical and health sciences research · 2013Article
- Screening obesity by direct and derived anthropometric indices with evaluation of physical efficiency among female college students of kolkata.Annals of medical and health sciences research · 2013Article
- Potential health impacts of hard water.International journal of preventive medicine · 2013Review
- Thyroid function in male infertility.Frontiers in endocrinology · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundExperimental unilateral cryptorchidism (ULC) and bilateral cryptorchidism (BLC) are excellent methods to study undescended testis in relation to spermatogenesis against a temperature gradient.
objectivesIn case of ULC, it is possible to compare the testicular functions between normal condition and cryptorchidism in the same animal, whereas BLC shows the necessity of testicular androgens for proper maintenance of reproductive structures and functions. MATERIALS AND
methodsIn the present study, experimental ULC and BLC was done on same-aged adult mature male mice and kept for 15 days and 30 days, respectively, to observe the changes due to the induced cryptorchidism on the different reproductive organs, viz., the testis and accessory sex organs along with epididymal sperm count. Reproductive tissues were collected from individual animals and histopathological studies of testis were done to investigate different cytological changes.
resultsThe size of the testes and accessory sex organs were found to be significantly reduced in BLC mice, whereas only testicular weight reduction was observed in ULC mice. Histopathological studies showed degenerative changes throughout the seminiferous tubules.
conclusionThus, the present investigation showed compensatory androgen production in ULC mice, whereas absence of androgen mediated reproductive functions in BLC animals.
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