ArticlePharmacognosy magazine2012
Study on chemical fingerprinting of crude and processed Atractylodes macrocephala from different locations in Zhejiang province by reversed-phase high-performance liquid chromatography coupled with hierarchical cluster analysis.
Article in Pharmacognosy magazine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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8 citing papers in PubMed, 21 citations in OpenAlex.
- Fungal diversity and network analysis in rhizosphere soil of Atractylodes macrocephala across different cultivation regions.Scientific reports · 2025Article
- Polysaccharides fromEvidence-based complementary and alternative medicine : eCAM · 2022Review
- Newly Generated Atractylon Derivatives in Processed Rhizomes ofMolecules (Basel, Switzerland) · 2020Article
- Antitumor, Antiviral, and Anti-Inflammatory Efficacy of Essential Oils fromMolecules (Basel, Switzerland) · 2019Article
- Recommendations towards standards for quantitative MRI (qMRI) and outstanding needs.Journal of magnetic resonance imaging : JMRI · 2019Review
- Chemical Differentiation of Genetically IdentifiedEvidence-based complementary and alternative medicine : eCAM · 2018Article
- Fast analysis of principal volatile compounds in crude and processed Atractylodes macrocephala by an automated static headspace gas chromatography-mass spectrometry.Pharmacognosy magazine · 2014Article
- Investigation of the Chemical Changes from Crude and Processed Paeoniae Radix Alba-Atractylodis Macrocephalae Rhizoma Herbal Pair Extracts by Using Q Exactive High-Performance Benchtop Quadrupole-Orbitrap LC-MS/MS.Evidence-based complementary and alternative medicine : eCAM · 2014Article
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10 authors at 2 institutions in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundIn China, Atractylodes macrocephala is mainly distributed in Zhejiang province. It is, therefore, desirable to determine a reliable and accurate methodology to differentiate the samples collected from Zhejiang province. Although some studies on the fingerprints of Atractylodes macrocephala using HPLC have been published, none of them compared the processed product of Atractylodes macrocephala from different areas of Zhejiang province. MATERIALS AND
methodsReversed-phase high-performance liquid chromatography (RP-HPLC) coupled with hierarchical cluster analysis was employed in the fingerprint analysis of Atractylodes macrocephala from Zhejiang province, China. The LC assay was performed on a reversed-phase C18 column with linear gradient elution using water and acetonitrile. The LC data showed considerable variation of chemical constituents among Atractylodes macrocephala populations.
results21 and 22 characteristic peaks in the 14 grants of Atractylodes macrocephala and its processed product were determined in samples from different habitats of Zhejiang province, respectively. Their chromatographic patterns were generally consistent although their contents of chemical compositions were greatly different. The results of hierarchical cluster analysis showed that the samples could be divided into four groups; it was able to select excellent resources from the groups.
conclusionThis was the first report of hierarchical cluster analysis of crude and processed Atractylodes macrocephala according to their chemical fingerprints and could be applied to the intrinsic quality control of crude and processed Atractylodes macrocephala. The processing technique of Atractylodes macrocephala through the pilot-scale experiment was first studied and is simple and suitable for prepared yin pian of Atractylodes macrocephala industrial manufacture.
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