ArticleInfection2014
Causes of death in HIV-infected patients from the Cologne-Bonn cohort.
Article in Infection, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02149004 (Translational Research Platform of the TTU HIV of the German Center for Infection Research), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Translational Research Platform of the TTU HIV of the German Center for Infection Research (DZIF)
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Interventions for tobacco use cessation in people living with HIV and AIDS.The Cochrane database of systematic reviews · 2016Pooled it
- Peer Navigation for Smoking Cessation in People With HIV Who Smoke: A Pilot Randomized Controlled Trial.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025Trial
- Mortality trends for diabetes mellitus, hypertension and cardiovascular disease among people living with and without HIV in Brazil during the COVID-19 pandemic, 2020-2022.HIV medicine · 2026Article
- Sexual quality of life among patients with lung cancer and people living with HIV: a cross-sectional study.Frontiers in psychology · 2026Article
- Incidence and risk factors for HIV-tuberculosis coinfection in the Cologne-Bonn region: a retrospective cohort study.Infection · 2024Article
- Article
- Peer navigation for smoking cessation in smokers with HIV: Protocol for a randomized clinical trial.Contemporary clinical trials · 2021Article
- Experiences With Smoking Cessation Attempts and Prior Use of Cessation Aids in Smokers With HIV: Findings From a Focus Group Study Conducted in Durham, North Carolina.AIDS education and prevention : official publication of the International Society for AIDS Education · 2021Article
- Inflammation in Relation to Intensity and Duration of Cigarette Smoking Among People Living with HIV.AIDS and behavior · 2021Article
- Smoking and Accelerated Lung Function Decline in HIV-Positive Individuals: A Secondary Analysis of the START Pulmonary Substudy.Journal of acquired immune deficiency syndromes (1999) · 2018Article
- Causes of death and mortality trends of all individuals reported with HIV/AIDS in Israel, 1985-2010.Journal of public health (Oxford, England) · 2018Article
- Cancer burden attributable to cigarette smoking among HIV-infected people in North America.AIDS (London, England) · 2018Observational
- Measles, mumps, rubella and VZV: importance of serological testing of vaccine-preventable diseases in young adults living with HIV in Germany.Epidemiology and infection · 2017Article
- Reductions in all-cause and cause-specific mortality among HIV-infected individuals receiving antiretroviral therapy in British Columbia, Canada: 2001-2012.HIV medicine · 2016Article
- Cause-Specific Mortality in HIV-Positive Patients Who Survived Ten Years after Starting Antiretroviral Therapy.PloS one · 2016Article
- Ageing with HIV: a multidisciplinary review.Infection · 2015Review
- Trends in hospital deaths among human immunodeficiency virus-infected patients during the antiretroviral therapy era, 1995 to 2011.Journal of hospital medicine · 2015Article
- The Cologne-Bonn cohort: lessons learned.Infection · 2015Review
- Cardiac Disease and HIV in Africa: A Case for Physical Exercise.The open AIDS journal · 2015Article
- Intestinal barrier dysfunction in HIV infection: pathophysiology, clinical implications and potential therapies.Infection · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCauses of death in human immunodeficiency virus (HIV)-infected subjects have changed in countries with high resources over the last several years. Acquired immunodeficiency syndrome (AIDS)-related diseases have become less prevalent, whereas deaths due to non-AIDS causes are increasing. The aim of the present study was to analyse causes of death in the Cologne-Bonn cohort.
methodsCauses of death from the Cologne-Bonn cohort between 2004 and 2010 were systematically recorded using the CoDe algorithm (The Coding Causes of Death in HIV Project).
resultsIn 3,165 patients followed from 2004 to 2010, 182 deaths occurred (5.7 %, 153 males, 29 females). The median age at the time of death was 47 years (range 24-85 years). The most frequent causes of death were AIDS-defining events (n = 60, 33 %), with non-Hodgkin lymphoma (NHL) (n = 29, 16 %) and infections (n = 20, 11 %) being the leading entities in this category. Non-AIDS malignancies accounted for 16 % (n = 29), non-HIV-related infections for 10 % (n = 18), cardiovascular diseases for 7 % (n = 14), suicide or accident for 4 % (n = 7) and liver diseases for 3 % (n = 5) of deaths (unknown n = 47, 26 %). Although the majority of patients (92.5 %) was on antiretroviral therapy (ART), only 50 % were virologically suppressed (HIV-RNA <50 copies/mL) and 44 % had a decreased CD4+ count (<200/μL) at their last visit before death.
conclusionOne-third of the causes of death in our cohort between 2004 and 2010 was AIDS-related. Since most of these deaths occur with severe immune suppression, they can possibly be prevented by the early diagnosis and treatment of HIV infection. Care providers must be aware of an increased risk for a broad range of diseases in HIV-infected patients and should apply appropriate preventive measures.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.