ReviewJournal of general internal medicine2014
Quality of care for patients with multiple chronic conditions: the role of comorbidity interrelatedness.
Review in Journal of general internal medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 114 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
114 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Global prevalence of multimorbidity among people living with type 2 diabetes: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Impact of multimorbidity on healthcare costs and utilisation: a systematic review of the UK literature.The British journal of general practice : the journal of the Royal College of General Practitioners · 2021Pooled it
- Pooled it
- Underlying mechanisms of complex interventions addressing the care of older adults with multimorbidity: a realist review.BMJ open · 2019Pooled it
- Psychiatric readmissions and their association with physical comorbidity: a systematic literature review.BMC psychiatry · 2017Pooled it
- Trial
- Quality performance and associated factors in Swiss diabetes care - A cross-sectional study.PloS one · 2020Trial
- The Relationship Between Subepidermal Moisture Assessment and Pain Measurements in Predicting Pressure Ulcer Development in At-Risk Adults.International wound journal · 2026Article
- Article
- Provision of medication prescription in a fracture liaison service did not diminish during COVID.Archives of osteoporosis · 2026Article
- Assessing real-world natural history of indolent systemic mastocytosis: A retrospective matched cohort study.The journal of allergy and clinical immunology. Global · 2026Article
- Trends in General Internal Medicine Patient and Care Complexity from 2017 to 2022 Across 21 Hospitals.Journal of general internal medicine · 2026Article
- Perceived Connections Between Personal Values and Health in High-Risk Patients with Multimorbidity: A Qualitative Study.Journal of general internal medicine · 2026Article
- Access and Perceived Quality of Care in US Adults with Multiple Chronic Conditions: MEPS 2019-2021.Journal of general internal medicine · 2026Article
- Intersectional patterns in dose-response associations between chronic diseases and mental health treatment utilization among New York City adults.Discover mental health · 2026Article
- A digital twin framework for predicting and simulating type 2 diabetes onset using retrospective lifestyle data.Frontiers in digital health · 2026Article
- The Mediating Roles of Self-Efficacy, Resilience, and Social Support in the Relationship Between Clinical Factors and Adaptation to Chronic Disease.Journal of multidisciplinary healthcare · 2026Article
- Forecasting multimorbidity in aging people with HIV using a microsimulation model.Communications health · 2026Article
- Health Risks Among Rural Aging Populations in China: A Cross-Sectional Study of Knowledge, Attitudes, and Practices in Chronic Disease Management.Risk management and healthcare policy · 2026Article
- Travel Distance and Its Impact on Wait Time for Positron Emission Tomography-Computed Tomography in Patients with Cancers.International journal of environmental research and public health · 2025Article
54 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Multimorbidity--the presence of multiple chronic conditions in a patient--has a profound impact on health, health care utilization, and associated costs. Definitions of multimorbidity in clinical care and research have evolved over time, initially focusing on a patient's number of comorbidities and the associated magnitude of required care processes, and later recognizing the potential influence of comorbidity characteristics on patient care and outcomes. In this article, we review the relationship between multimorbidity and quality of care, and discuss how this relationship may be mediated by the degree to which conditions interact with one another to generate clinical complexity (comorbidity interrelatedness). Drawing on established theoretical frameworks from cognitive engineering and biomedical informatics, we describe how interactions among conditions result in clinical complexity and may affect quality of care. We discuss how this comorbidity interrelatedness influences the value of existing quality guidelines and performance metrics, and describe opportunities to quantify this construct using data widely available through electronic health records. Incorporating comorbidity interrelatedness into conceptualizations of multimorbidity has the potential to enhance clinical and research efforts that aim to improve care for patients with multiple chronic conditions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.