Evidence map›Paper›PMID 24081382›Full record

ArticleJournal of materials science. Materials in medicine2014

Monetite and brushite coated magnesium: in vivo and in vitro models for degradation analysis.

Shaylin Shadanbaz, Jemimah Walker, Tim B F Woodfield, Mark P Staiger, George J Dias

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of materials science. Materials in medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Shaylin ShadanbazDepartment of Anatomy, University of Otago, Dunedin, New Zealand, shaylin.shadanbaz@anatomy.otago.ac.nz.
Jemimah Walker
Tim B F Woodfield
Mark P Staiger
George J Dias

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of magnesium (Mg) as a biodegradable metallic replacement of permanent orthopaedic materials is a current topic of interest and investigation. The appropriate biocompatibility, elastic modulus and mechanical properties of Mg recommend its suitability for bone fracture fixation. However, the degradation rates of Mg can be rapid and unpredictable resulting in mass hydrogen production and potential loss of mechanical integrity. Thus the application of calcium phosphate coatings has been considered as a means of improving the degradation properties of Mg. Brushite and monetite are utilized and their degradation properties (alongside uncoated Mg controls) are assessed in an in vivo subcutaneous environment and the findings compared to their in vitro degradation behaviour in immersion tests. The current findings suggest monetite coatings have significant degradation protective effects compared to brushite coatings in vivo. Furthermore, it is postulated that an in vitro immersion test may be used as a tentative predictor of in vivo subcutaneous degradation behavior of calcium phosphate coated and uncoated Mg.

Indexed as

Absorbable ImplantsAnimalsCalcium PhosphatesCoated Materials, BiocompatibleCorrosionMagnesiumMaleMaterials TestingMicroscopy, Electron, ScanningRatsRats, Inbred LewSurface Propertiescalcium phosphate, dibasic, anhydrouscalcium phosphate, dibasic, dihydrateCalcium PhosphatesCoated Materials, BiocompatibleMagnesium

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.