Evidence map›Paper›PMID 24081340›Full record

ArticleChest2013

Counterpoint: Should antipyretic therapy be given routinely to febrile patients in septic shock? No.

Anne M Drewry, Richard S Hotchkiss

Abstract readComment
In one paragraph

Article in Chest, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. The poikilothermic hypothesis of sepsis.Critical care (London, England) · 2026
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Anne M DrewryDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, MO. Electronic address: drewrya@anest.wustl.edu.
Richard S HotchkissDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, MO; Department of Surgery, Washington University School of Medicine, St. Louis, MO; Department of Medicine, Washington University School of Medicine, St. Louis, MO.

Funding

Washington University Institute of Clinical and Translational SciencesUL1TR000448 · NCATS · WASHINGTON UNIVERSITY · PI EVANOFF, BRADLEY A · 2012 to 2016
$41.4M
Prevention of Apoptotic Cell Death in Sepsis by BCL-2R37GM044118 · NIGMS · WASHINGTON UNIVERSITY · PI HOTCHKISS, RICHARD SAMUEL · 2003 to 2012
$5.1M
CELLULAR MECHANISMS OF SEPSIS AND ORGAN FAILURER01GM055194 · NIGMS · WASHINGTON UNIVERSITY · PI HOTCHKISS, RICHARD SAMUEL · 1997 to 2012
$4.7M
PREVENTION OF APOPTOTIC CELL DEATH IN SEPSIS BY BCL-2R01GM044118 · NIGMS · WASHINGTON UNIVERSITY · PI HOTCHKISS, RICHARD SAMUEL · 1992 to 2017
$2.7M
NCATS NIH HHS UL1 TR000448NCATS NIH HHS UL1TR000448NIGMS NIH HHS GM44118NIGMS NIH HHS GM55194NIGMS NIH HHS R01 GM044118NIGMS NIH HHS R01 GM055194NIGMS NIH HHS R37 GM044118
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AntipyreticsFeverHumansShock, SepticAntipyretics

Identifiers

PMID24081340
PMCPMC3787912

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.