Evidence map›Paper›PMID 24080637›Full record

ArticleThe American journal of tropical medicine and hygiene2013

Urban leptospirosis in Africa: a cross-sectional survey of Leptospira infection in rodents in the Kibera urban settlement, Nairobi, Kenya.

Jo E B Halliday, Darryn L Knobel, Kathryn J Allan, B Mark de C Bronsvoort, Ian Handel, Bernard Agwanda, Sally J Cutler, Beatrice Olack, Ahmed Ahmed, Rudy A Hartskeerl and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 4 pooled it
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 4 syntheses or guidelines pooled it, 66 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Genetic Characterization and Zoonotic Potential ofTropical medicine and infectious disease · 2025
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  9. Molecular detection and typing of pathogenicEpidemiology and infection · 2025
    Article
  10. Article
  11. Article
  12. Article
  13. First Molecular Detection of PathogensTropical medicine and infectious disease · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Prevalence of Leptospira Infection in Rodents from Bangladesh.International journal of environmental research and public health · 2019
    Article
  19. Article
  20. Molecular Detection ofEC microbiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jo E B Halliday
Darryn L Knobel
Kathryn J Allan
B Mark de C Bronsvoort
Ian Handel
Bernard Agwanda
Sally J Cutler
Beatrice Olack
Ahmed Ahmed
Rudy A Hartskeerl
M Kariuki Njenga
Sarah Cleaveland
Robert F Breiman

Funding

The Impact and Society Ecology of Bacterial Zoonoses in Northern Tanzania: UnderR01TW009237 · FIC · DUKE UNIVERSITY · PI CRUMP, JOHN ANDREW · 2011 to 2014
$1.7M
Biotechnology and Biological Sciences Research Council BB/J010367/1FIC NIH HHS R01 TW009237Medical Research Council G0902417Medical Research Council G0902417 94378Wellcome TrustWellcome Trust 081828/B/06/ZWellcome Trust 096400/Z/11/Z
6 · The paper itself

Abstract

Leptospirosis is a widespread but under-reported cause of morbidity and mortality. Global re-emergence of leptospirosis has been associated with the growth of informal urban settlements in which rodents are thought to be important reservoir hosts. Understanding the multi-host epidemiology of leptospirosis is essential to control and prevent disease. A cross-sectional survey of rodents in the Kibera settlement in Nairobi, Kenya was conducted in September-October 2008 to demonstrate the presence of pathogenic leptospires. A real-time quantitative polymerase chain reaction showed that 41 (18.3%) of 224 rodents carried pathogenic leptospires in their kidneys, and sequence data identified Leptospira interrogans and L. kirschneri in this population. Rodents of the genus Mus (37 of 185) were significantly more likely to be positive than those of the genus Rattus (4 of 39; odds ratio = 15.03). Questionnaire data showed frequent contact between humans and rodents in Kibera. This study emphasizes the need to quantify the public health impacts of this neglected disease at this and other urban sites in Africa.

Indexed as

AnimalsCross-Sectional StudiesDisease ReservoirsDNA, BacterialFemaleHumansKenyaLeptospiraLeptospira interrogansLeptospirosisMaleMiceMultivariate AnalysisPhylogenyRatsReal-Time Polymerase Chain ReactionDNA, Bacterial

Identifiers

PMID24080637
PMCPMC3854886
OpenAlexW2154167242

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.