ArticleGenomics, proteomics & bioinformatics2013
Generation of induced pluripotent stem cells with high efficiency from human umbilical cord blood mononuclear cells.
Article in Genomics, proteomics & bioinformatics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Harnessing Endogenous Plasticity Rather than Reprogramming of Mature Cells Will Advance Regenerative Medicine, Cancer Treatment and Rejuvenation.Stem cell reviews and reports · 2026Review
- Functional characterization and therapeutic potential of human umbilical cord blood mononuclear cells.Regenerative therapy · 2025Review
- Identification and Re-consent of Existing Cord Blood Donors for Creation of Induced Pluripotent Stem Cell Lines for Potential Clinical Applications.Stem cells translational medicine · 2022Article
- High glucose impairs osteogenic differentiation of embryonic stem cells via early diversion of beta-catenin from Forkhead box O to T cell factor interaction.Birth defects research · 2022Article
- Generation of Induced Pluripotent Stem Cells from Patients with Multiple MyelomaTurkish journal of haematology : official journal of Turkish Society of Haematology · 2021Article
- Contribution of Human Pluripotent Stem Cell-Based Models to Drug Discovery for Neurological Disorders.Cells · 2021Review
- Development, characterization, and hematopoietic differentiation of Griscelli syndrome type 2 induced pluripotent stem cells.Stem cell research & therapy · 2021Article
- Article
- Application of Cord Blood and Cord Blood-Derived Induced Pluripotent Stem Cells for Cartilage Regeneration.Cell transplantation · 2019Review
- Studying Human Neurological Disorders Using Induced Pluripotent Stem Cells: From 2D Monolayer to 3D Organoid and Blood Brain Barrier Models.Comprehensive physiology · 2019Review
- Establishment of a complex skin structure via layered co-culture of keratinocytes and fibroblasts derived from induced pluripotent stem cells.Stem cell research & therapy · 2018Article
- Osmotic modulation of chromatin impacts on efficiency and kinetics of cell fate modulation.Scientific reports · 2018Article
- Directed reprogramming of comprehensively characterized dental pulp stem cells extracted from natal tooth.Scientific reports · 2018Article
- Different Chondrogenic Potential among Human Induced Pluripotent Stem Cells from Diverse Origin Primary Cells.Stem cells international · 2018Article
- Accreditation of Biosafe Clinical-Grade Human Embryonic Stem Cells According to Chinese Regulations.Stem cell reports · 2017Article
- Induced pluripotent stem cell: A headway in reprogramming with promising approach in regenerative biology.Veterinary world · 2017Review
- Current status in cancer cell reprogramming and its clinical implications.Journal of cancer research and clinical oncology · 2017Review
- Cord blood cell-derived iPSCs as a new candidate for chondrogenic differentiation and cartilage regeneration.Stem cell research & therapy · 2017Article
- The Roles of Insulin-Like Growth Factors in Mesenchymal Stem Cell Niche.Stem cells international · 2017Review
- Generation of clinical-grade human induced pluripotent stem cells in Xeno-free conditions.Stem cell research & therapy · 2015Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Human induced pluripotent stem cells (iPSCs) hold great promise for regenerative medicine. Generating iPSCs from immunologically immature newborn umbilical cord blood mononuclear cells (UCBMCs) is of great significance. Here we report generation of human iPSCs with great efficiency from UCBMCs using a dox-inducible lentiviral system carrying four Yamanaka factors. We generated these cells by optimizing the existing iPSC induction protocol. The UCBMC-derived iPSCs (UCB-iPSCs) have characteristics that are identical to pluripotent human embryonic stem cells (hESCs). This study highlights the use of UCBMCs to generate highly functional human iPSCs that could accelerate the development of cell-based regenerative therapy for patients suffering from various diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.