ArticleBiochemistry2013
Tuning cofactor redox potentials: the 2-methoxy dihedral angle generates a redox potential difference of >160 mV between the primary (Q(A)) and secondary (Q(B)) quinones of the bacterial photosynthetic reaction center.
Article in Biochemistry, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed, 21 citations in OpenAlex.
- The Anionic States of Ubiquinone Characterized by Second-Order Approximate Coupled-Cluster Theory.Journal of computational chemistry · 2026Article
- Cryo-EM structures define ubiquinone-10 binding to mitochondrial complex I and conformational transitions accompanying Q-site occupancy.Nature communications · 2022Article
- Shedding Light on Primary Donors in Photosynthetic Reaction Centers.Frontiers in microbiology · 2021Review
- Redox potentials of ubiquinone, menaquinone, phylloquinone, and plastoquinone in aqueous solution.Photosynthesis research · 2017Article
- pKPhotosynthesis research · 2017Article
- Colin A. Wraight, 1945-2014.Photosynthesis research · 2016Article
- Redox potential tuning through differential quinone binding in the photosynthetic reaction center of Rhodobacter sphaeroides.Biochemistry · 2015Article
- Stigmatellin probes the electrostatic potential in the QB site of the photosynthetic reaction center.Biophysical journal · 2015Article
- The 2-Methoxy Group Orientation Regulates the Redox Potential Difference between the Primary (QThe journal of physical chemistry letters · 2014Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Only quinones with a 2-methoxy group can act simultaneously as the primary (QA) and secondary (QB) electron acceptors in photosynthetic reaction centers from Rhodobacter sphaeroides. (13)C hyperfine sublevel correlation measurements of the 2-methoxy in the semiquinone states, SQA and SQB, were compared with quantum mechanics calculations of the (13)C couplings as a function of the dihedral angle. X-ray structures support dihedral angle assignments corresponding to a redox potential gap (ΔEm) between QA and QB of ~180 mV. This is consistent with the failure of a ubiquinone analogue lacking the 2-methoxy to function as QB in mutant reaction centers with a ΔEm of ≈160-195 mV.
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Registered trials
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