Trial reportBMC geriatrics2013
Vertebral fractures and self-perceived health in elderly women and men in a population-based cross-sectional study: the Tromsø Study 2007-08.
Trial report in BMC geriatrics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 38 citations in OpenAlex.
- Health-related quality of life in men with osteoporosis: a systematic review and meta-analysis.Endocrine · 2021Pooled it
- Orthotics and taping in the management of vertebral fractures in people with osteoporosis: a systematic review.BMJ open · 2016Pooled it
- Health-Related Quality of Life in Men with Fractures and Fear of Falling in General Population: A Cross-Sectional Study.Journal of clinical medicine · 2025Article
- Health-related quality of life of men with primary osteoporosis and its changes after bisphosphonates treatment.BMC musculoskeletal disorders · 2023Article
- A summary of our recent evidence-based works on radiographic diagnostics of prevalent osteoporotic vertebral fracture in older men and women.Quantitative imaging in medicine and surgery · 2023Article
- Conversion of osteoporotic-like vertebral fracture severity score to osteoporosis T-score equivalent status: A framework study for older Chinese men.Osteoporosis and sarcopenia · 2023Article
- Vertebral Fractures Assessed by Dual-Energy X-Ray Absorptiometry and All-Cause Mortality: The Tromsø Study, 2007-2020.American journal of epidemiology · 2023Article
- An update of our understanding of radiographic diagnostics for prevalent osteoporotic vertebral fracture in elderly women.Quantitative imaging in medicine and surgery · 2022Article
- 'Healthier Chinese spine': an update of osteoporotic fractures in men (MrOS) and in women (MsOS) Hong Kong spine radiograph studies.Quantitative imaging in medicine and surgery · 2022Review
- Vertebral fracture: epidemiology, impact and use of DXA vertebral fracture assessment in fracture liaison services.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2021Article
- Radiographic osteoporotic vertebral fractures in elderly men: a brief review focusing on differences between the sexes.Quantitative imaging in medicine and surgery · 2020Review
- Underreporting characteristics of osteoporotic vertebral fracture in back pain clinic patients of a tertiary hospital in China.Journal of orthopaedic translation · 2020Article
- On the possibility of over-diagnosis of osteoporotic vertebral fracture at mid-thoracic level.Journal of thoracic disease · 2019Article
- Elderly males with or without existing osteoporotic vertebral fracture have much lower future vertebral fracture risk than elderly females: the MrOS (Hong Kong) year-4 follow-up spine radiograph study.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2019Article
- Informed communication with study subjects of radiographically detected osteoporotic vertebral deformity.Quantitative imaging in medicine and surgery · 2018Article
- All osteoporotically deformed vertebrae with >34% height loss have radiographically identifiable endplate/cortex fracture.Journal of orthopaedic translation · 2018Article
- Propofol and sevoflurane combined with remifentanil on the pain index, inflammatory factors and postoperative cognitive function of spine fracture patients.Experimental and therapeutic medicine · 2018Article
- Vertebral fractures and their association with health-related quality of life, back pain and physical function in older women.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHealth-related quality of life (HRQL) may be associated with increased mortality in the elderly. The effect of prevalent vertebral fractures on HRQL in elderly women and men is not well described. The purpose of this study was to examine the association between prevalent vertebral fractures and back pain, neck pain, and HRQL in elderly women and men, and to study possible gender differences in the reported pain and HRQL.
methodsInformation on prevalent vertebral fractures was ascertained by a vertebral fracture assessment (VFA) method (dual-energy X-ray absorptiometry (DXA), GE Lunar Prodigy) in 2887 women and men, mean age 65.4 (SD 9.4) who participated in the population-based Tromsø Study which was conducted in 2007-08. Bone mineral density (BMD; g/cm2) was measured by DXA at the femoral sites. Self-reported HRQL was assessed using the standardized measures EQ-5D-3 L and EQ VAS from the EuroQol Group. Lifestyle information was collected by questionnaires. The association between vertebral fractures and pain was analyzed using logistic regression, between vertebral fractures and EQ-5D-3 L and EQ VAS scores by multiple regression analyses.
resultsIn women, presence of vertebral fractures was associated with an increased risk of back pain with an OR of 1.76 (95% CI: 1.24 - 2.50) after adjustments for age, height, weight, and BMD. Women with vertebral fractures had lower EQ-5D-3 L scores (p < 0.001) than women without vertebral fractures, also after adjustments. These associations were not present in men. Type of fracture was not associated with EQ-5D-3 L scores, but increasing numbers (p < 0.001) and severity of fractures (p < 0.002) were associated with decreasing EQ-5D-3 L score in women.
conclusionPrevalent vertebral fractures are associated with increased risk of back pain and reduced HRQL in postmenopausal women, but not in men.
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Registered trials
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