ArticleEvoDevo2013
Evolution of eye development in the darkness of caves: adaptation, drift, or both?
Article in EvoDevo, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
48 citing papers in PubMed, 145 citations in OpenAlex.
- Subterranean Traits of the Visual System in Mandarin Voles (Lasiopodomys mandarinus): Structural Remodeling and Functional Degeneration.Integrative zoology · 2026Article
- HSP90 as an evolutionary capacitor drives adaptive eye size reduction via atonal.Nature communications · 2025Article
- Convergent Evolution in Amblyopsid Cavefishes and the Age of Eastern North American Subterranean Ecosystems.Molecular biology and evolution · 2025Article
- A Splicing Mutation in mitfa is Involved in the Depigmentation of Cavefish Triplophysa rosa.Molecular biology and evolution · 2025Article
- Parallel sensory compensation following independent subterranean colonization by groundwater salamanders (Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Light in the Darkness: Responses to Light and Diel Activity Rhythm in an Eyeless Cave Flatworm (Ecology and evolution · 2025Article
- Genomic signatures associated with the evolutionary loss of egg yolk in parasitoid wasps.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The emergence and loss of cyclic peptides inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Differentially expressed miRNAs offer new perspective into cave adaptation of Astyanax mexicanus.Annals of the New York Academy of Sciences · 2025Article
- Development and patterning of a highly versatile visual system in spiders.Proceedings. Biological sciences · 2025Article
- Stabilizing selection in an identified multisensory neuron in blind cavefish.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Environmental specificity of karst cave habitats evidenced by diverse symbiotic bacteria in Opiliones.BMC ecology and evolution · 2024Article
- From darkness to discovery: evolutionary, adaptive, and translational genetic insights from cavefish.Trends in genetics : TIG · 2024Review
- Unravelling the origins of boldness behaviour: a common garden experiment with cavefish (Royal Society open science · 2024Article
- Trait Loss in Evolution: What Cavefish Have Taught Us about Mechanisms Underlying Eye Regression.Integrative and comparative biology · 2023Review
- Genome Sequencing Provides Novel Insights into Mudflat Burrowing Adaptations in Eel GobyInternational journal of molecular sciences · 2023Article
- Developmental environment contributes to rapid trait shifts among newly colonized subterranean habitats.Zoological research · 2023Article
- Testing the predictive value of functional traits in diverse ant communities.Ecology and evolution · 2023Article
- Evolution of left-right asymmetry in the sensory system and foraging behavior during adaptation to food-sparse cave environments.BMC biology · 2022Article
- Novel genome sequence of Chinese cavefish (Triplophysa rosa) reveals pervasive relaxation of natural selection in cavefish genomes.Molecular ecology · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Animals inhabiting the darkness of caves are generally blind and de-pigmented, regardless of the phylum they belong to. Survival in this environment is an enormous challenge, the most obvious being to find food and mates without the help of vision, and the loss of eyes in cave animals is often accompanied by an enhancement of other sensory apparatuses. Here we review the recent literature describing developmental biology and molecular evolution studies in order to discuss the evolutionary mechanisms underlying adaptation to life in the dark. We conclude that both genetic drift (neutral hypothesis) and direct and indirect selection (selective hypothesis) occurred together during the loss of eyes in cave animals. We also identify some future directions of research to better understand adaptation to total darkness, for which integrative analyses relying on evo-devo approaches associated with thorough ecological and population genomic studies should shed some light.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.