Evidence map›Paper›PMID 24079076›Full record

ReviewPediatric endocrinology reviews : PER2013

Anorexia nervosa, obesity and bone metabolism.

Madhusmita Misra, Anne Klibanski

Abstract readReview
In one paragraph

Review in Pediatric endocrinology reviews : PER, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Article
  2. Syndecans in hematopoietic cells and their niches.American journal of physiology. Cell physiology · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. An overview of the metabolic functions of osteocalcin.Current osteoporosis reports · 2015
    Review
  12. An overview of the metabolic functions of osteocalcin.Reviews in endocrine & metabolic disorders · 2015
    Review
  13. Article
  14. Article
  15. Adiponectin is associated with bone strength and fracture history in paralyzed men with spinal cord injury.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Madhusmita MisraNeuroendocrine Unit, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA. mmisra@partners.org
Anne Klibanski

Funding

HARVARD CLINICAL AND TRANSLATIONAL SCIENCE CENTER (UL1)UL1RR025758 · NCRR · HARVARD MEDICAL SCHOOL · PI NADLER, LEE MARSHALL · 2008 to 2011
$91.4M
Effects of Anorexia Nervosa on Peak Bone MassR01DK062249 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI KLIBANSKI, ANNE · 2003 to 2015
$7.2M
Fat Mediated Modulation of Reproductive and Endocrine Function in Young AthletesR01HD060827 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI MISRA, MADHUSMITA · 2009 to 2013
$2.4M
NCRR NIH HHS UL1 RR025758NICHD NIH HHS 1R01 HD060827NICHD NIH HHS R01 HD060827NIDDK NIH HHS R01 DK062249
6 · The paper itself

Abstract

Anorexia nervosa and obesity are conditions at the extreme ends of the nutritional spectrum, associated with marked reductions versus increases respectively in body fat content. Both conditions are also associated with an increased risk for fractures. In anorexia nervosa, body composition and hormones secreted or regulated by body fat content are important determinants of low bone density, impaired bone structure and reduced bone strength. In addition, anorexia nervosa is characterized by increases in marrow adiposity and decreases in cold activated brown adipose tissue, both of which are related to low bone density. In obese individuals, greater visceral adiposity is associated with greater marrow fat, lower bone density and impaired bone structure. In this review, we discuss bone metabolism in anorexia nervosa and obesity in relation to adipose tissue distribution and hormones secreted or regulated by body fat content.

Indexed as

Anorexia NervosaBody CompositionBone and BonesChildHumansObesity

Identifiers

PMID24079076
PMCPMC4007116

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.