Evidence map›Paper›PMID 24078670›Full record

ArticleExperimental physiology2014

Postexercise syncope: Wingate syncope test and effective countermeasure.

Alisha N Lacewell, Tahisha M Buck, Steven A Romero, John R Halliwill

Open access · greenAbstract read
In one paragraph

Article in Experimental physiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 30 citations in OpenAlex.

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  14. The cardiovascular system after exercise.Journal of applied physiology (Bethesda, Md. : 1985) · 2017
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Alisha N LacewellJ. R. Halliwill: 122 Esslinger Hall, 1240 University of Oregon, Eugene, OR 97403-1240, USA. halliwil@uoregon.edu.
Tahisha M Buck
Steven A Romero
John R Halliwill
University of Oregon · US

Funding

Exercise, Histamine Receptors, & Vascular Health In AgingR01HL115027 · NHLBI · UNIVERSITY OF OREGON · PI HALLIWILL, JOHN R. · 2013 to 2016
$1.8M
NHLBI NIH HHS HL115027NHLBI NIH HHS R01 HL115027
6 · The paper itself

Abstract

Altered systemic haemodynamics following exercise can compromise cerebral perfusion and result in syncope. As the Wingate anaerobic test often induces presyncope, we hypothesized that a modified Wingate test could form the basis of a novel model for the study of postexercise syncope and a test bed for potential countermeasures. Along these lines, breathing through an impedance threshold device has been shown to increase tolerance to hypovolaemia, and could prove beneficial in the setting of postexercise syncope. Therefore, we hypothesized that a modified Wingate test followed by head-up tilt would produce postexercise syncope, and that breathing through an impedance threshold device (countermeasure) would prevent postexercise syncope in healthy individuals. Nineteen recreationally active men and women underwent a 60 deg head-up tilt during recovery from the Wingate test while arterial pressure, heart rate, end-tidal CO2 and cerebral tissue oxygenation were measured on a control day and a countermeasure day. The duration of tolerable tilt was increased by a median time of 3 min 48 s with countermeasure in comparison to the control (P < 0.05), and completion of the tilt test increased from 42 to 67% with the countermeasure. During the tilt, mean arterial pressure was greater (108.0 ± 4.1 versus 100.4 ± 2.4 mmHg; P < 0.05) with the countermeasure in comparison to the control. These data suggest that the Wingate syncope test produces a high incidence of presyncope, which is sensitive to countermeasures such as inspiratory impedance.

Indexed as

AdolescentAdultArterial PressureCarbon DioxideCerebrovascular CirculationExerciseFemaleHeart RateHemodynamicsHumansMaleOxygenPostureRespirationSyncopeTilt-Table TestCarbon DioxideOxygen

Identifiers

PMID24078670
PMCPMC3947357
OpenAlexW2141599575

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.