Trial reportSocial cognitive and affective neuroscience2014
Opioid receptor blockade and warmth-liking: effects on interpersonal trust and frontal asymmetry.
Trial report in Social cognitive and affective neuroscience, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 39 citations in OpenAlex.
- Opioids and social bonding: Effect of naltrexone on feelings of social connection and ventral striatum activity to close others.Journal of experimental psychology. General · 2020Trial
- Naltrexone alters responses to social and physical warmth: implications for social bonding.Social cognitive and affective neuroscience · 2019Trial
- Opioids and social bonding: naltrexone reduces feelings of social connection.Social cognitive and affective neuroscience · 2016Trial
- Blocking opioids attenuates physical warmth-induced feelings of social connection.Emotion (Washington, D.C.) · 2015Trial
- The Selective Dopamine D2 Blocker Sulpiride Modulates the Relationship Between Agentic Extraversion and Executive Functions.Cognitive, affective & behavioral neuroscience · 2021Article
- The Association of Drug-Use Characteristics and Active Coping Styles With Positive Affect in Patients With Heroin-Use Disorder and Methamphetamine-Use Disorder During the COVID-19 Pandemic.Frontiers in public health · 2021Article
- Frontal EEG Asymmetry and Middle Line Power Difference in Discrete Emotions.Frontiers in behavioral neuroscience · 2018Article
- Naltrexone alters the processing of social and emotional stimuli in healthy adults.Social neuroscience · 2016Article
- Gender Interacts with Opioid Receptor Polymorphism A118G and Serotonin Receptor Polymorphism -1438 A/G on Speed-Dating Success.Human nature (Hawthorne, N.Y.) · 2016Article
- Article
- Effects of oxycodone on brain responses to emotional images.Psychopharmacology · 2014Article
- Dopamine modulates frontomedial failure processing of agentic introverts versus extraverts in incentive contexts.Cognitive, affective & behavioral neuroscience · 2014Article
- Is love right? Prefrontal resting brain asymmetry is related to the affiliation motive.Frontiers in human neuroscience · 2013Article
- Implications for Reward Processing in Differential Responses to Loss: Impacts on Attachment Hierarchy Reorganization.Personality and social psychology review : an official journal of the Society for Personality and Social Psychology, IncArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The emotion 'warmth-liking' (WL) associated with feelings of affection and acceptance is regularly activated in social contexts. WL has been suggested to be more closely related to the consummatory phase of post-goal attainment positive affect than to pre-goal attainment positive affect/approach motivation and to be partly mediated by brain opioids. To validate these assumptions we employed film/imagery to induce either a neutral emotional state or WL in female participants after intake of either placebo or the opioid antagonist naltrexone. Dependent variables were emotion self-report, interpersonal trust (TRUST, i.e. a behavioral indicator of WL) and frontal asymmetry (i.e. an electroencephalogram (EEG) indicator of approach motivation/behavioral activation). We found that participants reported more WL in the placebo/WL group than in the placebo/neutral group and both naltrexone groups. In addition, TRUST increased in the WL group after placebo, but not after naltrexone, and this pattern was reversed in the neutral control groups. Consequently, opioid blockade suppressed or even reversed the effects of the WL induction on the levels of self-report and behavior, respectively. In addition, we observed reduced relative left-frontal asymmetry in the WL (vs neutral) group, consistent with reduced approach motivation. Overall, these results suggest opioidergic influences on WL and TRUST and reduced approach motivation/behavioral activation for the positive emotion WL.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.