SynthesisHuman reproduction update
Childbearing attitudes and decisions of young breast cancer survivors: a systematic review.
Synthesis in Human reproduction update. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 7 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 7 syntheses or guidelines pooled it, 99 citations in OpenAlex.
- Mapping and comparing the quality of life outcomes in childhood and adolescent and young adult cancer survivors: an umbrella review and future directions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Pooled it
- Psychosocial experiences of breast cancer survivors: a meta-review.Journal of cancer survivorship : research and practice · 2024Pooled it
- Perspectives of Young Women With Gynecologic Cancers on Fertility and Fertility Preservation: A Systematic Review.The oncologist · 2022Pooled it
- A meta-review of qualitative research on adult cancer survivors: current strengths and evidence gaps.Journal of cancer survivorship : research and practice · 2019Pooled it
- Unintended Pregnancy: A Systematic Review of Contraception Use and Counseling in Women With Cancer.Clinical journal of oncology nursing · 2017Pooled it
- Healthcare professionals' views on discussing fertility preservation with young cancer patients: a mixed method systematic review of the literature.Psycho-oncology · 2017Pooled it
- Fertility and parenthood issues in young female cancer patients--a systematic review.Journal of cancer survivorship : research and practice · 2014Pooled it
- Global patterns and risk factors of breast cancer in women under 35: a population-based study.Breast (Edinburgh, Scotland) · 2026Article
- Gravidity and Fertility Desires of Female Cancer Survivors and Age-Matched Controls: Using the National Survey of Family Growth.Journal of adolescent and young adult oncology · 2026Article
- Achieving Pregnancy After Early Hormone Receptor-Positive Breast Cancer: Recent Evidence and Clinical Considerations.Cancers · 2026Review
- Fertility information support experiences of spouses of young breast cancer patients in China: a qualitative study.BMJ open · 2025Article
- Fertility Information Perceptions and Needs of People with Cancer, Their Family Members, and Caregivers.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Article
- The prevalence of parental cancer history and in vitro fertilization utilization.Journal of the National Cancer Institute · 2025Article
- Exploring fertility preservation in AYA cancer survivors: Information needs and post-cancer challenges.PloS one · 2025Article
- Trends in breast cancer mortality attributable to metabolic risks in Chinese women from 1990 to 2019: an age-period-cohort analysis.Frontiers in oncology · 2024Article
- Disparities in fertility preservation use among adolescent and young adult women with cancer.Journal of cancer survivorship : research and practice · 2023Article
- The lived experiences of pregnancy planning after breast cancer in women of childbearing age: A phenomenological study.Asia-Pacific journal of oncology nursing · 2023Article
- Intervening on women's health for rural young breast cancer survivors: A study protocol.Contemporary clinical trials · 2023Article
- Exploration of fertility and early menopause related information needs and development of online information for young breast cancer survivors.BMC women's health · 2022Article
- Decisional Regret in Female Oncofertility Decision Making-An Integrative Narrative Review.Cancers · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundYoung breast cancer survivors often need to deal with adverse effects of treatments on fertility and complex reproductive decisions. In this systematic review, we highlight what is known about childbearing and parenthood attitudes and decisions of young breast cancer survivors from their own perspective.
methodsWe conducted manual and electronic searches on Pubmed, PsychInf and CINAHL databases for articles, published in English between 1 January 1990 and 31 October 2012, that assessed childbearing, pregnancy and parenthood attitudes/decisions of female breast cancer survivors (premenopausal and/or <50 years old). Eligible articles were classified into quantitative studies, qualitative studies and mixed methods studies. Data from each study were individually extracted by all the authors, and standardized tables were created and discussed to ensure congruence of the information extracted.
resultsOf the 493 publications identified in PubMed (results are presented for PubMed searches as the other databases did not yield any new relevant papers), 8 met the inclusion criteria, in addition to 2 publications retrieved manually. A total of 10 studies provided information on pregnancy and parenthood attitudes and decisions, in addition to risks and benefits of childbearing after breast cancer. Survivors had mixed attitudes towards the issue. Fear associated with future pregnancy was reported, namely the risk of cancer recurrence. However, for many survivors, pregnancy and parenthood can represent normalcy, happiness and life fulfilment.
conclusionsChildbearing after breast cancer is an important issue for survivors. Future larger and prospective studies should be implemented to increase certainty of conclusions of current research. Clinicians may benefit from a deeper understanding of the importance of pregnancy and parenthood to survivors in order to provide the needed educational and psychosocial support services, overcome misinformation and better assist women with their fertility-related decisions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.