Evidence map›Paper›PMID 24077936›Full record

SynthesisLung2014

Effects of exercise training on sleep apnea: a meta-analysis.

Imran H Iftikhar, Christopher E Kline, Shawn D Youngstedt

2 registry-linked trialsOpen access · greenAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in Lung, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 99 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
99citing papers in PubMed, 9 pooled it
8.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05311280 naunknown statusnot on this mapstarted 2022, after this paper: background citation

The Effect of High Intensity Interval Exercise and Myofunctional Therapy on Obstructive Sleep Apnea: a Randomized Clinical Controlled Trial

TypeinterventionalSponsorTaoyuan General HospitalRan2022 to 2022Enrolled40ConditionsObstructive Sleep ApneaArmshigh intensity interval training plus myotherapy, home exercise plus myotherapy
NCT05390138 naunknown statusnot on this mapstarted 2022, after this paper: background citation

A Smart Sleep Apnea Self-management Support Programme(4S) to Improve Apnea Severity and Cardiovascular Health - A Pragmatic Randomized Controlled Trial With Mixed-method Evaluation

TypeinterventionalSponsorThe University of Hong KongRan2022 to 2024Enrolled120ConditionsObstructive Sleep ApneaArmsSmart Sleep Apnea Self-management Support Programme (4S), General Hygiene Information (GH)
3 · Its place in the literature

Who cites it

99 citing papers in PubMed, 9 syntheses or guidelines pooled it, 239 citations in OpenAlex.

  1. Effectiveness of aerobic exercise training in patients with obstructive sleep apnea: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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  5. Exercise training and depression and anxiety in musculoskeletal pain patients: a meta-analysis of randomized control trials.Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2023
    Pooled it
  6. Effects of Exercise on Patients with Obstructive Sleep Apnea: A Systematic Review and Meta-Analysis.International journal of environmental research and public health · 2022
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39 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Imran H Iftikhar
Christopher E Kline
Shawn D Youngstedt
SleepMed · USUniversity of Pittsburgh · USWm. Jennings Bryan Dorn VA Medical Center · US

Funding

Translational Research Training in Sleep MedicineT32HL082610 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Daniel J. Buysse, PETER L FRANZEN · 2007 to 2026
$5.8M
MULTI-SITE RCT FOR BP CONTROL IN HTN AFRICAN AMERICANSR01HL078566 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI OGEDEGBE, OLUGBENGA G. · 2004 to 2011
$4.5M
Chronic Moderate Sleep Restriction in Older Long and Older Average SleepersR01HL095799 · NHLBI · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI IRWIN, MICHAEL R, JEAN-LOUIS, GIRARDIN · 2011 to 2015
$3.8M
NHLBI NIH HHS HL082610NHLBI NIH HHS HL78566NHLBI NIH HHS R01 HL078566NHLBI NIH HHS R01 HL095799NHLBI NIH HHS T32 HL082610
6 · The paper itself

Abstract

backgroundSeveral studies have shown a favorable effect of supervised exercise training on obstructive sleep apnea (OSA). This meta-analysis was conducted to analyze the data from these studies on the severity of OSA (primary outcome) in adults. Secondary outcomes of interest included body mass index (BMI), sleep efficiency, daytime sleepiness and cardiorespiratory fitness.

methodsTwo independent reviewers searched PubMed and Embase (from inception to March 6, 2013) to identify studies on the effects of supervised exercise training in adults with OSA. Pre- and postexercise training data on our primary and secondary outcomes were extracted.

resultsA total of 5 studies with 6 cohorts that enrolled a total of 129 study participants met the inclusion criteria. The pooled estimate of mean pre- to postintervention (exercise) reduction in AHI was −6.27 events/h (95 % confidence interval [CI] -8.54 to -3.99; p < 0.001). The pooled estimates of mean changes in BMI, sleep efficiency, Epworth sleepiness scale and VO2 peak were -1.37 (95 % CI −2.81 to 0.07; p = 0.06), 5.75 % (95 % CI 2.47-9.03; p = 0.001), -3.3 (95 % CI -5.57 to -1.02; p = 0.004), and 3.93 mL/kg/min (95 % CI 2.44-5.42; p < 0.001), respectively.

conclusionsThis meta-analysis shows a statistically significant effect of exercise in reducing the severity of sleep apnea in patients with OSA with minimal changes in body weight. Additionally, the significant effects of exercise on cardiorespiratory fitness, daytime sleepiness, and sleep efficiency indicate the potential value of exercise in the management of OSA.

Indexed as

Exercise TherapySleepBody Mass IndexHumansOxygen ConsumptionPhysical FitnessSeverity of Illness IndexSleep Apnea SyndromesTreatment Outcome

Identifiers

PMID24077936
PMCPMC4216726
OpenAlexW2048431494

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.