Evidence map›Paper›PMID 24077861›Full record

ArticleJournal of assisted reproduction and genetics2013

Accumulation of oocytes from a few modified natural cycles to improve IVF results: a pilot study.

Ermanno Greco, Katarzyna Litwicka, Cristiana Arrivi, Maria Teresa Varricchio, Daniela Zavaglia, Cecilia Mencacci, Maria Giulia Minasi

Abstract readComparative Study
In one paragraph

Article in Journal of assisted reproduction and genetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ermanno Greco
Katarzyna Litwicka
Cristiana Arrivi
Maria Teresa Varricchio
Daniela Zavaglia
Cecilia Mencacci
Maria Giulia Minasi

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the role of co-transfer of embryos derived from vitrified oocytes accumulated during the previous modified natural cycles and an embryo developed from the last one as an alternative to repetitive single embryo transfer ina fresh modified natural cycle.

methodsThirty-six patients underwent ICSI procedure with three frozen natural oocytes supplemented by a fresh one obtained from the fourth modified natural cycle. Thirty-one controls received at least three consecutive single embryo transfer in a fresh modified natural cycle.

resultsIn the study group the oocyte retrieval, survival and total fertilization rate were 73.0 %, 78.1 %, and 64.5 %, respectively. Fifty-two embryos were transferred in 29 transfers. In the control group the oocyte retrieval and fertilization rate was 77.4 % and 83.7 %, respectively. Fifty single embryo transfers were performed. Of a total 14 pregnancies obtained in the study group 10 were defined as clinical and 4 as abortions. In the control group a total of 8 single clinical pregnancies and 2 miscarriages were encountered. The overall (20.0 % vs 48.2 %) and the clinical (16.0 % vs 34.4 %) pregnancy rate were significantly higher in the study group having cumulative embryo transfer following the oocyte accumulation.

conclusionsThese data demonstrate that the co-transfer of embryos derived from vitrified oocytes accumulated during the previous modified natural cycles and an embryo developed from the last fresh modified natural cycle assure an excellent clinical outcome with the overall and clinical pregnancy rate significantly higher compared to the repetitive single embryo transfer in a fresh modified natural cycle.

Indexed as

Fertilization in VitroSperm Injections, IntracytoplasmicAdultCase-Control StudiesCryopreservationEmbryo TransferFemaleFertilizationHumansMiddle AgedOocytesPilot ProjectsPregnancyVitrification

Identifiers

PMID24077861
PMCPMC3879935

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