ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2014
Predictors of anxiety and depression in people with colorectal cancer.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 74 citations in OpenAlex.
- Effects of Psycho-education Interventions on Colorectal Cancer Patients: A systematic review and meta-analysis.Journal of cancer education : the official journal of the American Association for Cancer Education · 2023Pooled it
- Symptom Experiences in Colorectal Cancer Survivors After Cancer Treatments: A Systematic Review and Meta-analysis.Cancer nursingPooled it
- Anxiety, depression, quality of life and the mediating role of psychological flexibility: A study on Spanish cancer patients.Scientific reports · 2025Trial
- Effect of mindfulness yoga on anxiety and depression in early breast cancer patients received adjuvant chemotherapy: a randomized clinical trial.Journal of cancer research and clinical oncology · 2022Trial
- Quality of life and illness perceptions in patients with breast cancer using a fasting mimicking diet as an adjunct to neoadjuvant chemotherapy in the phase 2 DIRECT (BOOG 2013-14) trial.Breast cancer research and treatment · 2021Trial
- The relation of illness perceptions to stress, depression, and fatigue in patients with chronic lymphocytic leukaemia.Psychology & health · 2016Trial
- Factors associated with anxiety in colorectal cancer survivors: a scoping review.Journal of cancer survivorship : research and practice · 2026Article
- The relationship between perceived stress and depression in colorectal cancer patients: the mediating role of illness perception and the moderating role of self-efficacy.Frontiers in oncology · 2026Article
- The Impact of Bevacizumab and Chemotherapy on Quality of Life in Metastatic Colorectal Cancer Patients.Healthcare (Basel, Switzerland) · 2023Article
- Prevalence and predictors of psychological distress among patients with thyroid cancer during transitional period in China: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Dignity and psychosocial related variables in elderly advanced cancer patients.BMC geriatrics · 2022Observational
- Early-Onset Colorectal Cancer Survival Differences and Potential Geographic Determinants Among Men and Women in Utah.American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting · 2022Article
- Coping Strategies in Elderly Colorectal Cancer Patients.Cancers · 2022Review
- Nomogram to Predict the Risk of Postoperative Anxiety and Depression in Colorectal Cancer Patients.International journal of general medicine · 2022Article
- Prevalence and determinants of depression up to 5 years after colorectal cancer surgery: results from the ColoREctal Wellbeing (CREW) study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021Article
- Serial Assessment of Depression and Anxiety by Patients and Providers in Women Receiving Chemotherapy for Early Breast Cancer.The oncologist · 2021Article
- Financial burden and quality of life among early-onset colorectal cancer survivors: A qualitative analysis.Health expectations : an international journal of public participation in health care and health policy · 2019Article
- Cost-effectiveness of mini-laparotomy in patients with colorectal cancers: A propensity scoring matching approach.PloS one · 2019Article
- Reduction in social activities mediates the relationship between diarrhea and distress in rectal/anal cancer survivors.Psycho-oncology · 2018Article
- Emotional distress and dysfunctional illness perception are associated with low mental and physical quality of life in Chinese breast cancer patients.Health and quality of life outcomes · 2017Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
Abstract
backgroundPeople living with colorectal cancer are at risk of anxiety and depression. We investigated what factors were most highly associated with these.
methodsFour hundred and ninety-six people with colorectal cancer completed the Hospital Anxiety and Depression Scale (HADS). Data on functioning, symptoms, illness perceptions and social difficulties were collected by questionnaire. Case-note-identified disease, treatment and co-morbidity data were recorded. Multiple logistic regression identified factors independently predictive of anxiety and depression caseness.
resultsSelf-reported history of anxiety/depression predicted anxiety but not depression caseness. Depression caseness predicted anxiety caseness (p = 0.043), as did poorer self-reported cognitive functioning (p = 0.001), dyspnoea (p = 0.015) or diarrhoea (p = 0.021), reporting a high negative life and emotional impact (p < 0.001) and having difficulties with finance (p = 0.007). Having neo-adjuvant radiotherapy increased the odds of depression caseness (p = 0.007), as did poorer physical (p = 0.007), cognitive (p < 0.001) and social (p < 0.001) functioning, having constipation (p = 0.011), reporting a high negative life and emotional impact (p < 0.001), having difficulties with personal care (p = 0.022) and communicating with others (p = 0.014).
conclusionLevels of anxiety caseness were similar to those of non-clinical samples, but depression caseness was higher, particularly in those who had received neo-adjuvant radiotherapy. Most factors associated with possible or probable depression may be modified with appropriate intervention.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.