ArticleCancer control : journal of the Moffitt Cancer Center2013
Cutaneous leiomyosarcoma: treatment and outcomes with a standardized margin of resection.
Article in Cancer control : journal of the Moffitt Cancer Center, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 61 citations in OpenAlex.
- Cutaneous Leiomyosarcoma of the Skin: An Updated Review of Epidemiology, Pathogenesis, and Management.International journal of dermatology · 2026Review
- Prognosis and Follow-Up Recommendations for Subcutaneous and Dermal Leiomyosarcoma: Local Recurrence, Metastasis, and Overall Survival in a Danish Nationwide Cohort of 661 Patients.Journal of surgical oncology · 2025Article
- Primary cutaneous leiomyosarcoma: demographics and survival benefit of surgical management in a US population.Proceedings (Baylor University. Medical Center) · 2025Article
- Clinical Variables Influencing Outcomes in Patients with Atypical Intradermal Smooth Muscle Neoplasms (Formerly Cutaneous Leiomyosarcomas): Single-Institution Study of 95 Surgical Patients.Annals of surgical oncology · 2024Article
- Frontal cutaneous leiomyosarcoma: A case report and review of the literature.SAGE open medical case reports · 2023Article
- Cutaneous soft tissue sarcomas: survival-related factors.Archives of dermatological research · 2022Review
- Primary Cutaneous Leiomyosarcoma of the Lower Extremity: A Case Report and Literature Review.Cureus · 2021Article
- Primary leiomyosarcoma of the skin: a comprehensive review on diagnosis and treatment.Medical oncology (Northwood, London, England) · 2018Review
- Delayed diagnosis of dermal leiomyosarcoma mimicking keloid scar.BMJ case reports · 2018Article
- Cutaneous leiomyosarcoma on the trunk: An unusual presentation with an aggressive course - Case report and review of literature.The Pan African medical journal · 2018Review
- Periorbital leiomyosarcoma treated by means of conventional surgery and frontal myocutaneous flap.Anais brasileiros de dermatologia · 2017Article
- Soft tissue sarcoma of the extremities: pending questions on surgery and radiotherapy.Radiation oncology (London, England) · 2016Review
- Leiomyosarcoma of the Face.Archives of craniofacial surgery · 2014Article
- Grade of Primary Cutaneous Leiomyosarcoma Dictates Risk for Metastatic Spread and Disease-Specific Mortality.Cancer control : journal of the Moffitt Cancer CenterArticle
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundCutaneous leiomyosarcoma is primarily a low-grade malignancy that affects elderly male Caucasians. It is a rare dermal-based tumor for which treatment algorithms have been poorly defined.
methodsWe retrospectively reviewed the use of a median 1-cm margin for resection to treat patients with cutaneous leiomyosarcoma referred for treatment between 2005 and 2010.
resultsThirty-three patients with cutaneous leiomyosarcoma were treated. Of these, 76% were male, 97% were Caucasian (median age: 63.5 years), and 67% of tumors were located on the extremities. Preoperative staging was negative for distant metastasis in all patients. A majority of the tumors (88%) were low grade (median size: 1.3 cm). All of the tumors were positive for smooth-muscle actin. A total of 94% of patients underwent primary surgical resection with a median margin of 1 cm. Final resection margin was negative in 97% of patients. Adjuvant radiotherapy was used in 15%. No metastatic spread or recurrences were present, and 100% of patients were alive at last follow-up (median: 15.5 months).
conclusionsGood oncological control and excellent outcomes are possible with a 1-cm resection margin in most cases of cutaneous leiomyosarcoma.
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